In today’s era when technology is changing with each passing day, the automobile industry is also undergoing unprecedented changes, and electric vehicles (EV) are becoming a new technology hotspot. Xiaomi Group, a technology giant that started with smart phones, has now officially entered this highly competitive field. In March 2021, Xiaomi announced that it would enter the automobile industry. Since then, the progress of Xiaomi Automobile has been receiving much attention. Now, with less than half a year to go before the mass production of Xiaomi’s first car, Lei Jun, founder, chairman and CEO of Xiaomi Group, announced that it will hold a Xiaomi car technology conference at 2 pm this Thursday, which will be the first official appearance of Xiaomi car.

The technical conference of Xiaomi Automobile is a milestone, which marks the official debut of Xiaomi in the automobile industry. Although the theme of the conference is technology rather than products, it still shows that Xiaomi has made remarkable progress in automotive technology and is ready to share these achievements with the public and the industry. Lei Jun’s circle of friends further emphasized the importance of this point, and his words revealed his confidence in Xiaomi’s automobile technology.

Before this conference, Xiaomi Auto’s official social media account has been launched, which indicates that Xiaomi Auto’s brand building and marketing activities have started, and Xiaomi is preparing to enter the vast auto market. In the latest Catalogue of New Energy Vehicles Exempted from Vehicle Purchase Tax issued by the Ministry of Industry and Information Technology, the information of Xiaomi’s first model SU7 was officially disclosed, which further deepened the public’s expectation for Xiaomi.

The technical parameters of Xiaomi SU7 show Xiaomi’s ambition in electric vehicle technology. Two kinds of battery packs with different capacities and different cruising ranges, as well as technical support to BYD and Contemporary Amperex Technology Co., Limited, two major battery manufacturers, all show Xiaomi’s in-depth research and cooperation in battery technology of electric vehicles. In particular, the options of different battery capacity and different vehicle kerb quality provide responses to different market demands.

Judging from Lei Jun’s promise, Xiaomi Automobile will show cutting-edge technology and high-level manufacturing capability when it is released. This commitment is not only a strong signal to consumers, but also shows the automobile industry that Xiaomi is a new competitor with foresight and strength. Xiaomi’s brand influence and successful experience in the field of intelligent hardware may bring new innovation and vitality to the automobile industry.

All in all, the upcoming technical conference of Xiaomi Automobile is a key moment in Xiaomi’s journey into the automobile industry. It will not only show Xiaomi’s latest achievements in automotive technology, but also lay the foundation for the market launch of Xiaomi’s first mass-produced car. With the official appearance of Xiaomi Automobile, we have reason to expect how Xiaomi will show its innovative spirit and technical strength in this new field full of challenges and opportunities.

Promote Hangzhou to build a highland of outdoor industry quality in China

On the morning of March 22nd, 2024, CLE2024 China (Hangzhou) Outdoor Camping Life Exhibition ("CLE 2024 Hangzhou Exhibition") kicked off at Hangzhou International Expo Center with a simple but creative outdoor fashion show. From March 22nd to 24th, more than 200 exhibitors and more than 300 brands participated in the event, and the organizer also organized 10 themes and over 80 heavyweight events to be staged in 9 major spaces, showing the overall development trends of outdoor industry in China.

Since 2023, CLE Hangzhou Exhibition every spring has become an important industry activity of outdoor industry in China. According to the exhibition data released by the organizing committee a few days ago, during the three-day exhibition, all exhibitors will, together with industry practitioners, enthusiasts, relevant competent departments and major Internet platforms, comprehensively explain all kinds of industry information of China’s outdoor sports industry in equipment manufacturing, platform sales trends, and the direction of choosing people to bring goods, share the experience of organizing and operating camps and outdoor activities, carry out international exchanges, fully experience the latest equipment for outdoor catering and outdoor travel, and feel the complete and full outdoor culture.

With the theme of "Connecting Outdoor Life", this CLE 2024 Hangzhou Exhibition focuses on the e-commerce, cross-border transaction and internationalization of outdoor industry, which provides a new industry idea for the sustainable development of outdoor industry in China. According to incomplete statistics, there are nearly 1,000 people who have signed up for CLE 2024 Hangzhou Exhibition, and the total number of fans has exceeded 150 million, accounting for about 1/3 of the outdoor population in China. At the same time, exhibitors and camp owners from more than ten countries including Russia, Mongolia, Kazakhstan, Singapore, Malaysia, Canada, Japan, Australia and the Middle East visited the exhibition site.

Focusing on promoting and popularizing outdoor culture is another major feature of CLE 2024 Hangzhou Exhibition. A brief history of camping, the first general book in China to introduce the 150-year development of outdoor camping industry, was launched at this CLE 2024 Hangzhou Exhibition, and the creator and publishing agency China Academy of Fine Arts Press signed a sale for the audience on the spot. At the same time, the CLE Camping Museum was jointly established by several exhibitors at the exhibition, which provided a space for industry visitors and enthusiasts to understand the historical development of outdoor camping.

As a manufacturing highland in China, Zhejiang is also a gathering area of outdoor camping industry. At the CLE 2024 Hangzhou Exhibition, the audience can also see the product displays from Sanmen, the capital of China jackets, and several industrial belts.

Since 2020, Hangzhou has become the benchmark of exquisite camping and outdoor leisure life in China, and many representative camps have gathered around the city. In three days, CLE 2024 Hangzhou Exhibition brought together industry practitioners from all over the country and around the world to focus on the status quo and challenges of China’s outdoor industry, and put forward solutions and solutions from the perspective and methods of China, which will further boost Hangzhou’s construction into a high-quality outdoor industry in China.

Attachment: Summary of CLE 2024 Hangzhou Exhibition

CLE 2024 Hangzhou Exhibition Site Activity Arrangement

Time: March 22-24, 2024

Venue: 3F, Hangzhou International Expo Center

I. Layout of the Exhibition

CLE2024 Exhibitor Booth Distribution Map

Second, the 9 major activity spaces of the exhibition

In order to present the outdoor camping lifestyle in an all-round way and create a better on-site environment for industry exchange and docking, nine activity spaces were set up in the venue of CLE 2024 Hangzhou Exhibition, namely:

"grow good business" outdoor forum area

"City Outdoor" Picnic, Coffee, Wine and Chill Moment

Aesthetic natural education of "Learn Shan Ye with pleasure"

"Outdoor Partner" Lifestyle Community

Outdoor life model room "wilderness home"

Outdoor camping sea ecological zone

CLE& Xiaohongshu blogger guest contact area

Product selection area for bloggers with goods

CLE outdoor camping museum

III. Summary of participating brands

CLE2024 Exhibitor Brand List

IV. CLE 2024 Hangzhou Exhibition Schedule

CLE2024 exhibition tour guide

V. Contents of "Planting Good Business" Outdoor Forum Area

01 Shan Ye audio • Music scene

02 "Natural Opening" Outdoor Fashion Show

Jointly launch outdoor fashion show with KOL, anchor with goods and brand exhibitors, and open the preface of 2024CLE.

Look at the 150-year camping history — — Press conference of the new book "A Brief History of Camping"

The first book in China that systematically introduces the 150-year history of camping, A Brief History of Camping, was released and recommended by the promoters and practitioners of outdoor lifestyle in Nomori territory.

Decryption of China Outdoor Brand E-commerce Operation — — Domestic e-commerce platform sharing

"Tik Tok" Tik Tok E-commerce Outdoor Camping 2024 Trend Release

Dong Yunlu Doris Dong-Head of Business Transportation in Camping Industry of Tik Tok E-commerce Brand Group

"Little Red Book", "Everything grows in the wind" Little Red Book Sports Outdoor Inspiration Marketing Sharing

Mingjun-Xiaohongshu Commercial Fashion Clothing Industry Sports Outdoor Integrated Marketing Expert

"Tmall" 2024 Tmall camping trend sharing

Cherish life-head of Tmall camping

New businesses in "Aauto Quicker" have new operations and new growth.

Yu Ailin-Aauto Quicker is the operation director of "Official Assistant of Magnetic Taurus" and the operation director of "Jinniu Classroom".

The growth trend of outdoor sports with "getting things"

Muyi-Dewu Outdoor Category Operation Experts

05 CLE outdoor brand promotion special session

"Outdoor Power Supply and Outdoor Electricity Consumption Ecology"

Leng Xiaowei-General Manager of Shenzhen Yizu Innovation Technology Co., Ltd.

"It’s just the right time to go out to sea-avoid the winner’s thinking of getting involved and going out"

Li Hualin-CEO of WebTV Asia Grape Media Greater China

"Introduction of the Famous City of Jacket Clothing in Sanmen County"

Li Lujia-Deputy Director of Sanmen County Investment Promotion Center

"To help outdoor products go to sea, how to save logistics costs from the source? 」

Wang Letian-General Manager of Xiyou Logistics East China Branch

"Canadian outdoor lifestyle"

Grace-Founder of Smypark Canada Limited

"Canadian health functional food SunDrench brand sharing meeting"

Shangduoli (Hangzhou) International Food Technology Co., Ltd.

"SP1KE New Technology Released for External Protection of Customers"

Canada SP1KE company

"The Next Fifteen Years of Black Deer"

Ye Xiao-Black Deer Brand Manager

"Keep Walking: The Road of Fire Maple Research and Development"

Qin Yu-Head of Brand R&D of Huofeng

"Introduction of Nujiang outdoor sports industry project".

Zhang Xuelian-Deputy Director of Nujiang Education and Sports Bureau

"Introduction of throwing Frisbee"

An Chenran-Founding Partner/General Manager of Wing Kun Frisbee

"Star Navigator: A Journey of Astronomy and Space Exploration in Mars Camp"

Feng Jiang-Mars camp co-founder camp director and general manager of Cold Lake Astronomy.

"Open your heart and fly, and you will naturally respond."

Wei Xiaoliang-I fly outdoor COO

"pot ring brand sharing"

Guo quan Shi hui

"brand sharing of Harajuku self-operated factory"

Harajuku

"What else can I eat for a healthy outdoor life? See how camping scenes keep pace with "food"

Amanda-ELMJOY Yu zhiyu brand promoter

"Wolf Brand Story"

Ma Haozhe-Founder CEO of Wolf

06 Outdoor Wind Blows the World — — There are new tricks for cross-border going to sea, and nine platforms face each other.

Deep analysis of all categories of Amazon outdoor sports in "Amazon opens stores worldwide"

Sunny Zhou-Senior Manager of Key Account Development and Operation Management of Amazon

"eBay" E-way peers, everything is fine. Introduction of Bay-eBay2024 platform and outdoor category sharing.

Zhang Haoyuan-Business Development Manager of eBay Greater China

Introduction of "TikTok Shop" Full Hosting Mode and Promotion of Outdoor Sports Category

Chen Yongkuo-Outdoor Investment Manager of Tiktok Shop Cross-border E-commerce Campaign

"Wal-Mart" is outdoors in "Wo", and it is just the right time to go to sea.

Weiwei Chen-Wal-Mart Global E-commerce Strategic Channel Development Consultant

"Coupang" and Coupang, Nuggets "Sports Outdoor" New Business Opportunities

May Gao-Coupang, Head of Investment Promotion in East China

Introduction of "Lazada" Full Trusteeship Mode and Promotion of Outdoor Sports Category

Dai Guisheng-Lazada, Investment Manager of Outdoor Sports in Full Trust

"Meikeduo" went out to sea to dig gold in Latin America.

Max-Mercado China East China Business and Regional Development Manager

"Shopee" makes every possibility of outdoor camping in Southeast Asia.

Elaine (Pang Yiyue)-Shopee Investment Promotion and Incubation Manager

"Lotte Japan" went out to sea in Japan and chose Lotte Japan, a cross-border e-commerce treasure platform.

Wu Feifei-Investment Manager of Lotte Group Shenzhen Branch, Japan

07 2024 Spring Camping Conference of Pot Circle Food Exchange

One-stop solution promotion of pot camping life, first release of new pot products, investment promotion policy of pot camping shop, cooperation and signing of 100 camping plans, etc.

08 Let’s meet — — All-in-one exchange meeting of cultural, sports and tourism

The sharing of diversified outdoor life, the introduction of China Road-Zhejiang Station, the signing ceremony of 2024 Association’s self-driving market operation and government cooperation, and the promotion of local self-driving and camping destinations.

09 camp product and content innovation — — Campsite building logic

International experience of combining youth camp and holiday camp in "international outdoor emerging market"

Former President of Valery Kostin-ICF International Camp Association

Valerii Dolgikh-President of Russian Camp Association

Abdumukhtorov Anvar Akramovich-Director of Leisure and Rehabilitation Department of Uzbekistan

Bymba Chultem-Chairman of Mongolian Camp Association

Duan Diandian-Secretary General of ICE Camp Research Institute

How can outdoor camping empower rural revitalization?

Manager of Baoxin-Xiaohangkeng Camp

"Camp Planning and Design" The Core Elements of Camp Planning and Design

Dai Zheng-good morning, founder of Yesu

"Camp diversification case" Camping new era, camp diversification development model

Jingliang-Founder of Camp Club

"Chain Camp Case" Hi King Camp, Chain Development

Cui lianbo-hi, founder of King chain camp

Construction of camp products of "comprehensive camp operation case"

Tang Wei-Niulu Camping & Founder of Niulu Outdoor Education, Ph.D. in Tourism Hotel Management, Hong Kong Polytechnic University, and chinese mountaineering association Youth Outdoor Education Tutor.

Looking for the most beautiful camp in China to see the trend of camping and outdoor sports

Zhao Jingwen-Founder of Camping Season

How to plan a competitive campsite in the era of consumption degradation?

Mingli-General Manager of Shanghai Kemu Design

10 Connecting Outdoor Life — — Lifestyle innovation

"Cross-border Outdoor" Australian Camping Mode Sharing

TIM CUTLER – AOA

"outdoor research" outdoor research scene and content (Camping in Trent)

Kelly-Head of Admissions, Trent University, China

"Outdoor travel" Vala may be more free.

Fang Fang-co-founder of Vala

"Outdoor Climbing" into No Man’s Land, Antarctic Exploration and Protection

Bin Sun-Founder of National Mountaineer Peak Outdoor Sports School

How much face can the new trend of "outdoor wearing" bring?

Founder of Bi Yiran-UPPERVOID’s Second Latitude

VI. Other supporting activities

(A) interactive punching activities

"CLE 2024 Hangzhou Exhibition", in conjunction with Xiaohongshu and Tik Tok Platform, organized a number of interactive and punching activities in the same period.

(B) On-site outdoor activities experience and teaching

"CLE 2024 Hangzhou Exhibition" has joined more than 10 outdoor sports, outdoor education and outdoor experience institutions, and there are nearly 20 outdoor activities and community activities on the spot to open the experience to the audience.

(3) Pet-friendly

CLE 2024 Hangzhou Exhibition continued the pet-friendly policy. All kinds of pets that meet the pet management policy of Hangzhou can enter the venue after reporting in advance. The organizing committee of CLE 2024 Hangzhou Exhibition also set up a special pet-friendly area to serve the visitors’ pet storage.

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Xinhua News Agency, London, November 1st (Reporter Zhang Wei) Arsenal and Manchester United both lost to opponents from the same Premier League on the 1st, and missed the quarterfinals of the English League Cup.

Arsenal played against West Ham United in London on the same day, and fell behind in the first half because of White’s careless own goal. "Arsenal" coach arteta bluntly said after the game that the ball directly influenced the development direction of the game. Since then, Arsenal, which has an absolute advantage in possession of the ball, has never been able to make a breakthrough. On the contrary, Kaddos added another point five minutes after the West Ham United Easy Side, extending the lead to 2-0. In the 60th minute, Bowen hit a long-range shot outside the penalty area. It wasn’t until the final stoppage time that Arsenal were pulled back by substitute Odegard, and the score was fixed at 1-3.

On November 1st, Arsenal coach Arteta looked depressed after the game. Xinhua News Agency/Reuters

Manchester United, who just suffered a home defeat in the Manchester derby last weekend, continued to sink at Old Trafford. Against Newcastle United, they conceded two goals in a row in the first half. In the 60th minute, Willock got rid of the defense with the ball in the frontcourt and hit the door to help the Magpie achieve a 3-0 victory.

Newcastle, who lost to the "Red Devils" in the Carling Cup final last season, took revenge, and their quarter-final opponent will be Chelsea who beat Blackburn 2-0 on the same day.

In addition, Liverpool beat Bournemouth 2-1 with goals from Gakpo and Nunez, and the quarterfinals will face West Ham United.

Recently, Yan Ning, a famous structural biologist, announced that he would resign from Princeton University and set up the Academy of Medical Sciences in Shenzhen. In response to the latest research that she will focus on when she returns to China, she said that the discovery of structural biology is of great significance to the pharmaceutical industry, including the research on the interaction between drugs and hormones, which has more implications for drug development and disease treatment.

Yan Ning said, for example, that through the method of structural biology, scientists saw for the first time that two commonly used drugs used protein as a "scaffold", which directly "side by side" affected the normal function of protein.

Technological change promotes the development of structural biology.

Protein, as the scaffold and main substance of human tissues and organs, plays an important role in human life activities. In the cell, a large number of protein elements form the molecular machines, which performs important molecular processes in the cell through the interaction of protein, including the cell’s response to the external environment and the internal environment, and also forms a signal transduction network system with the interaction of protein as a link.

Structure By studying the three-dimensional structure, dynamic process and biological function of biological macromolecules, biology can provide more details of protein interaction and real-time dynamic process, thus helping scientists to understand molecular mechanism and explore the pathogenesis of diseases related to macromolecular dysfunction.

The development of biology not only contributes to the discovery of drugs, but also affects the research fields of life sciences including biochemistry, cell biology, genetic development, neurobiology, microbiology and pathopharmacology.

The development of science and technology has been promoting the progress of structural biology. In 2017, the Nobel Prize in Chemistry was awarded to cryoelectron microscopy, which can greatly improve the efficiency of analyzing the atomic resolution three-dimensional structure of large protein complexes; Moreover, researchers can freeze biomolecules in motion and visualize their motion process.

This breakthrough has brought a perfect storm to the field of structural biology. In recent years, important breakthroughs have been made in the field of life sciences. The work of China scientists such as Cheng Yifan, Shi Yigong, Yang Maojun and Liu Zhengfeng has also benefited from this technology. They have analyzed the important complex structure of atomic resolution. In addition, the enzyme that produces the protein that leads to Alzheimer’s syndrome was analyzed by cryomicroscope.

In August, 2015, Shi Yigong’s research team published an article in Nature, reporting the three-dimensional electron microscope structure of human γ -secretase with a resolution of 3.4 angstrom, and studying the function of the pathogenic mutant of γ -secretase based on the structure analysis, which provided an important foundation for understanding the working mechanism of γ -secretase and the pathogenesis of Alzheimer’s disease.

In February, 2020, after the outbreak of COVID-19, the research team of West Lake University successfully analyzed the full-length structure of novel coronavirus receptor ACE2 for the first time by using cryo-electron microscopy, which helped the research and development of drugs in COVID-19.

What does AI predict protein folding change?

With the help of artificial intelligence technology, DeepMind, a subsidiary of Google, recently announced 220 million kinds of protein structures predicted by AlphaFold software, which shocked the field of structural biology, because it indicates that artificial intelligence enterprises have begun to "truly hand over the power of Al to scientists all over the world".

Scientists compare the significance of this disruptive breakthrough with the human genome project. In the 1990s, when the Human Genome Project began to take shape, scientists realized that it was not enough to master the base arrangement of genes, but also to know the protein, the product of genes.

Shi Yigong, academician of China Academy of Sciences, structural biologist and president of West Lake University, commented on AlphaFold’s work: "Its accurate prediction of protein structure is the greatest contribution of artificial intelligence to the scientific field, and it is also one of the most important scientific breakthroughs made by mankind in the 21st century."

Shi Yigong once told China Business News: "AlphaFold represents the world’s leading artificial intelligence protein organization prediction system." At the same time, he said, China’s high-tech enterprises are catching up, expecting to bring surprises to the world in the near future.

He also said that the improvement of the accuracy of protein structure prediction will greatly benefit the pharmaceutical industry. "Artificial intelligence prediction of protein structure provides an important foundation for drug design and optimization. The structure of drug target proteins combined with all small molecule drugs can almost be wiped out by AlphaFold. " Shi Yigong said.

In the opinion of some scientists, although AlphaFold’s work is shocking, the accuracy of drug research and development prediction is not enough. Professor Liu Zhijie, executive director of iHuman Institute, Shanghai University of Science and Technology, told the First Financial Reporter: "It has been a long time to predict the protein structure. Now the accuracy of the prediction is definitely getting higher and higher, but it still hasn’t reached the precision of crystal structure."

Liu Zhijie First Financial News told the reporter that the crystal structure is the most accurate, and now artificial intelligence can predict the protein folding with the accuracy of electron microscope and nuclear magnetic resonance. In addition, because there are thousands of structures in protein, the difficulty of analysis is different. "If some protein sequences are similar to the known structure of artificial intelligence, it is easier to predict." Liu Zhijie said.

However, he still believes that with the continuous improvement of the prediction accuracy of protein folding, it will play a more important role in the field of life sciences in the future. "If the current prediction can reach the accuracy of electron microscope, some drugs can already be designed. Drug design is the biggest application field of artificial intelligence protein folding prediction." Said to Liu Zhijie First Financial Reporter.

Others think that with the development of artificial intelligence, there may not be so many structural biologists in the future. "Many researchers who do structural biology are actually more like technical service personnel. The more people there are, the more structures that can be analyzed. Therefore, in essence, a large part of their work depends on manpower. Now with AI, it is true that a large number of people who do structural biology have changed careers." A virus researcher told the First Financial News reporter.

However, for top structural biologists such as Shi Yigong, technology is only a powerful support for the "top brain", which can help them realize more ideas. "Every conscientious biologist should know how to make good use of the structural prediction of artificial intelligence." Shi Yigong said.

Professor Michael Levitt, winner of the Nobel Prize in Chemistry in 2013, told China Business News: "I think many structural biologists are not only doing structural research, but also doing a lot of work on protein function and drug research and development, just like Professor Yan Ning. Artificial intelligence only liberates a part of traditional manpower, but the progress of science still needs to rely on the smartest human brain. I’m afraid that artificial intelligence alone will not work. "

In recent years, a number of AI pharmaceutical companies have also been born in China. In this regard, Ewing Nan, academician of Chinese Academy of Sciences and president of Beijing Institute of Scientific Intelligence, pointed out to the First Financial Reporter: "The emergence of AI for Science research paradigm is an important historical opportunity for scientific and technological innovation, which not only expands the capability boundary of data-driven and physical model-driven models, but also is expected to promote the organic combination of the two, provide theoretical basis for further solving practical problems, and greatly narrow the distance between scientific research and practical application."