Rock Wubai took the stage wildly, wearing a war robe to endorse the game (picture)






wubai



wubai


  In order to welcome the online game "Wind and Fire Journey" on the stage, the spokesperson of the Rock King Wu Bai specially rode a cross-country beach bike that symbolizes the spirit of wind and fire, entered the venue handsomely, and held the holy fire to open the game listing. Wu Bai also donned a dozen kilograms of combat robes and paint to shoot TV commercials a few days ago.


  Wu Bai, a rock king with a full schedule and work schedule, also specially produced the theme music "Wind and Fire" for the game this time. This powerful music will also be included in his upcoming album in October. In addition, the game Shinkansen specially asked the original factory to make Wu Bai NPC (non-player character) in the game, so that players can also get in touch with Wu Bai in the game. Wu Bai NPC will not only talk to the player, but also help the player restore vitality or strength in a timely manner.

Editor in charge: Sun Jie

Andy Lau’s version of "Di Renjie" has characteristics, and Carina Lau’s diamond jewelry steals the show

        On the evening of the 24th, Tsui Hark, Andy Lau, Carina Lau, Li Bingbing, Deng Chao, Yang Shoucheng, Shi Nansheng, and others attended the charity premiere in Times Square. As the celebration on the main creators’ stage drew to a close, emotional fans broke through the defense and rushed onto the stage, and Hua Zai signed autographs for the other party without hesitation to resolve the crisis. 

        In the past, celebrities would have the phenomenon of "colliding shirts" when attending events, and in recent years, the phenomenon of "colliding shirts" in film and television works is also everywhere. There are different versions of Di Renjie in the TV series. Now that Andy Lau has once again interpreted this historical figure, it is inevitable that he has a mind set. In this regard, the director has given Hua Zai as much space as possible to put aside the existing image and play his own detective, which is unique.

        In the posters that have been exposed in the film, Liu Jialing’s version of Wu Zetian’s eyebrows have caused a lot of discussion in the community. The styling director Yu Jiaan revealed that the inspiration was based on Dunhuang murals, while the director Xu Ke said: "This is completely different from all the women’s makeup looks in the Tang Dynasty that the audience saw in the past. Only Wu Zetian has the strength and courage to try this kind of look and makeup, because she is unique." In this regard, the actor Liu Jialing is also very satisfied with her look.

        Carina put on 15 million sponsored diamond jewelry to steal the limelight, Leung Chaowei is filming in the mainland, Carina said that she will be concerned about it in her heart, revealing that she has contact every day. Mentioning that her friend Faye Wong often comes to Hong Kong to buy clothes, Carina said that she often goes to the mainland and can’t accompany each other, and will go to Beijing to support concerts later. In addition, when it comes to the same release, ask Andy if he thinks he is a strong competitor? He said he is not afraid of competition, thinking that there are different movies released every week, and everyone will be happy to receive 300 million at the box office.

Next page More wonderful pictures

Taxi collective strike in Yongdeng County, Gansu Province

  Xinhuanet Lanzhou, November 10 (reporter, Wang Zhiheng, Guo Gang) On November 10, due to dissatisfaction with the large number of local illegal rental vehicles interfering with the passenger market, a collective strike of hundreds of taxis took place in Yongdeng County, Lanzhou City, Gansu Province.


  The reporter rushed to the county seat of Yongdeng County, Gansu Province, and saw that the suspended taxis were neatly placed on both sides of the road at the gate of the Yongdeng County Transportation Bureau. It was rare to see taxis driving on the street, which caused great inconvenience to the residents of Yongdeng County.


  Ma Jiangshan, a representative of the strike taxi driver, told reporters that the strike began at 9 a.m., and there were more than 280 taxis operating legally in the county, and more than 160 taxis participated in the strike that day.


  Ma Jiangshan said that the main reason for the strike is the increasing number of "motorcycles" and taxis operating illegally in the local area, which has seriously affected the income of legal taxis. According to their understanding, there are currently more than 700 illegally operated "motorcycles" and taxis in the county seat. These illegal vehicles and legal taxis compete for customers and engage in malicious competition at low prices, resulting in a sharp drop in their income. At present, the daily operating income is only about 20 yuan, which can only support basic living.


  Chen Yongshun, a representative of the strike drivers, said that since 2006, three taxi operating companies have been established in Yongdeng County. Some local farmers and laid-off workers have invested more than 30,000 yuan to buy vehicles and join the three companies to engage in local rental business. At first, they had a monthly income of thousands of yuan. Later, as more and more taxis were operating illegally, the income of legal taxis became less and less. Now the daily income is less than half of what it was at the beginning. They have reported the situation to the county traffic bureau and the public security bureau many times, but the problem cannot be solved. They have no choice but to take measures to stop the operation in order to protect their legitimate rights and interests.


  Guo Shiling, director of the Yongdeng County Transportation Bureau, told reporters that the illegal taxi operators are mainly some private car owners in the county seat. In order to subsidize their own car expenses, they secretly engage in illegal passenger-carrying business, and the operating time and location change at any time. Even if they are caught by law enforcement officers of the transportation department, according to the relevant provisions of the "Regulations of the People’s Republic of China on the Administration of Road Transport", they can only be fined, but not revoked driving licenses and driver’s licenses, which will not play a deterrent role. As a result, there is a vicious circle of illegal taxis being "caught and fined, and fined and released" by the transportation department.


  Guo Shiling said that although the traffic management department has difficulties in law enforcement, such as difficulty in obtaining evidence and limited penalties, the county transportation bureau has been stepping up its crackdown. On Nov. 5, just before the taxi strike, the county transportation bureau, together with the Yongdeng County Traffic Police Brigade and the Yongdeng County Administrative Law Enforcement Bureau, issued the "Implementation Plan for Regulating County Traffic Order" to carry out "100-day rectification actions" to crack down on illegal activities, including illegal taxi operations.


  As of press time, taxis in Yongdeng had not resumed normal operations. Ma Jiangshan and other strike drivers said they would continue to strike until the county authorities could give them a clear time to crack down on illegal taxis.


 





















































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Guangzhou Sex Culture Festival, sexy underwear shows as the focus (Photo) After the man killed someone, his relatives called the police, and the court sentenced him to five years

Editor in charge: Li Dan

New Knowledge | Take a photo of the "behemoth" at the center of the galaxy

This is the first photo of the black hole at the center of the Milky Way released by astronomers on May 12. Xinhua News Agency

At 21:00 on May 12, Beijing time, the Event Horizon Telescope (EHT) cooperation organization held a press conference in seven cities around the world, including Shanghai, and announced the first photo of the supermassive black hole (Sagittarius A *) at the center of the Milky Way. For the first time in human history, the true face of the center of the Milky Way has been revealed.

This black hole photo was co-organized by the Event Horizon Telescope (EHT) and "taken" through a network of radio telescopes distributed around the world. Its release gives evidence that Sagittarius A * is the black hole in the center of the Milky Way, providing valuable clues for understanding this "behemoth" that is generally believed to inhabit the center of most galaxies. Its birth opened a new chapter in human exploration of the black hole in the center of the Milky Way.

Getting to know black holes for the first time

For the mysterious and vast universe, human beings are always full of imagination, and most of them come from the most primitive curiosity of human beings. With the development of science and technology, many imaginings have become scientific predictions, and through the unremitting exploration of generations of scientists, they have further become reality.

Modern astronomy tells us that the beautiful Milky Way we see at night is actually a flat disk-shaped spiral galaxy composed of hundreds of billions of stars. And our solar system, as an ordinary member of it, revolves around the center of the Milky Way 27,000 light-years away from the center of the Milky Way.

The "Galactic Center" was located in the direction of Sagittarius, which was covered with a large amount of gas and dust. It was difficult to observe in the visible light band, and the infrared and radio bands with longer wavelengths were less affected, which became the main way to study the "Galactic Center".

In 1933, when Carl Jansky of Bell Labs published a paper announcing the discovery of radio radiation possibly originating from the center of the Milky Way galaxy, it was the first time that humans had captured radio waves in the depths of space, but scientists at the time knew nothing about the secrets behind this intense radio radiation. Over the next three decades, Jansky’s findings were not only confirmed, but also traces of intense radio radiation were found in other, more distant galaxies.

Similar findings have led theorists to make bold predictions that galaxies harbor supermassive black holes at their centers, which are sources of intense radio radiation.

Black holes are cosmic celestial bodies that make many people curious. But few people really understand this cosmic "monster".

What is a black hole? "In layman’s terms, a black hole is actually the remains of a huge star," said Qin Ruiqiang, president of the Hebei Astronomy Amateur Association.

According to the introduction, the interior of a star is constantly undergoing thermonuclear reactions. When a star ages, it uses up the fuel in the center due to thermonuclear reactions, and there is not much energy produced by the center. At this time, it can no longer bear the huge weight of the shell. Therefore, under the weight of the shell, the core begins to collapse, and matter will inexorably "march" towards the center point. At this time, a supernova explosion will occur for a long time, until finally the star forms a star with a volume close to infinity and an almost infinite density, which is a black hole.

To fly from Earth to space, a rocket needs to reach a speed of 7.9 kilometers per second. As the mass of the Earth continues to increase, its surface attractive force will also increase, and the rocket will escape the Earth at an increasing speed. When this speed reaches 300,000 kilometers per second, nothing can escape the celestial body, including light.

A black hole is this celestial object that even light cannot escape, and this region is known as the black hole’s event horizon.

Inside, no light can escape, and all matter and mass gather at the singularity at the center of the black hole, where the curvature of space-time is infinite and the attractive force is infinite. Once inside the event horizon, all the laws of physics we know about the world break down.

In 1971, astronomers Nader Lindenberg and Martin Rees first predicted that there was a supermassive black hole at the center of the Milky Way. Because of the nature of black holes, it cannot be directly observed. But as the black hole swallows other matter, it forms an accretion disk, in which a large amount of matter rotates, rubs, and warms around the black hole, making the temperature here reach millions of degrees Celsius and appear very bright.

Black holes are one of the rarest cases in the history of science, developed to the point of exhaustion as a mathematical model without any observational evidence to prove their theory correct. In the early 20th century, black holes became widely known by Einstein’s general theory of relativity, but scientists did not discover the first black hole until 1970.

Although scientists have long simulated the appearance of black holes in supercomputers, they have long hoped to take a picture of them.

Photographing a black hole

With the continuous advancement of technology, humans can finally take pictures of black holes. Scientists chose two supermassive black holes as "models".

Released this year is Sagittarius A *, the supermassive black hole at the center of the Milky Way, 27,000 light-years from Earth and more than 400 times the mass of the Sun. The black hole image released in 2019 is from the galaxy M87, which is farther and larger, 55 million light-years away from Earth and 6.50 billion times the mass of the Sun.

"People observe these two black holes from the earth, they are very small, and the apparent diameter of the ring structure is only about 40 to 50 microarc seconds." Qin Ruiqiang introduced that a microarc second is about the size of the period at the end of an article on the earth when viewed from the moon. The two black holes seem to be a "doughnut" on the surface of the moon 380,000 kilometers away from the ground.

Such a small apparent diameter challenges the angular resolution of telescopes.

"Angular resolution is a term that describes the capabilities of a telescope," Mr. Qin said. The smaller the angular resolution, the better the telescope’s ability to distinguish distant celestial bodies, and the clearer the images we can obtain.

The optical telescope is affected by the lens process and the earth’s atmosphere, and its resolution is weak. Even the 39.3-meter European Extremely Large Telescope under construction has a theoretical limit angular resolution of only 1,000 microarcseconds, which is still far from 50 microarcseconds.

Therefore, scientists thought of radio telescopes.

The aperture of a single radio telescope can reach tens of meters or even hundreds of meters. Although the resolution is much lower than that of optical telescopes of the same aperture due to its longer observation wavelength, scientists can use a VLBI (Very Long Baseline Interferometry) technology to form two or more radio telescopes into a larger aperture radio telescope, and improve the resolution by increasing the aperture.

According to reports, the black hole photos released in 2019 were also contributed by the Shanghai Tianma Telescope. It formed the East Asia VLBI Network with several stations in South Korea and Japan to conduct observations. The addition of the Tianma Telescope has improved the quality of East Asia VLBI maps by 53%.

Although Sagittarius A * is closer to Earth, photographing it is much more difficult than M87 *. The achievement was achieved by the whims of more than 300 researchers from 80 research institutions around the world.

The EHT collaboration "combined" eight radio telescopes in six geographic locations around the world to form a so-called "Event Horizon Telescope" with unprecedented sensitivity and resolution.

In 2017, the eight telescopes, which travel north to Spain and south to the South Pole, cast a "big net" at selected targets to "retrieve" massive amounts of data to give us a picture of what a black hole looks like. But the observation window left to scientists is very short, only about 10 days per year.

In addition to the limitation of observation time, photographing black holes is also extremely demanding in terms of weather conditions. "Water in the atmosphere has a significant impact on this observation band, and water affects the intensity of radio waves, which means that precipitation can interfere with observations." As a result, experts say, the eight telescopes are located in areas with high altitudes, very little rainfall and a very high probability of sunny days.

In addition, successful imaging requires all telescopes to be fully synchronized in time. During observations, each radio telescope collects and records radio wave signals from the vicinity of the target black hole, which are integrated to obtain an image of the event horizon. To ensure signal stability, the EHT uses atomic clocks to ensure that the signals it collects and records are synchronized in time.

Chi-kwan Chan, a scientist at the Steward Observatory in the United States, the Department of Astronomy and the Institute of Data Science at the University of Arizona, has described the difficulty of observing Sagittarius A * this way: "The surrounding gas is rotating around Sagittarius A * and M87 * at a high speed at almost the speed of light. It takes a few days to several weeks for the gas to circle M87 *, but for the much smaller Sagittarius A *, the gas can circle once in a few minutes. This means that as the EHT observes Sagittarius A *, the brightness and pattern of the gas surrounding the supermassive black hole are also changing rapidly over time. Taking a picture of Sagittarius A * is a bit like taking a clear picture of a puppy chasing its tail."

In the future, EHT will make a black hole "movie"

Using existing images of two black holes with masses more than 1,500 times different, scientists can further examine the attractive forces in extreme environments.

The photo of Sagittarius A * was made from a combination of many photos extracted from the EHT observation data in 2017. Since then, in 2018, 2020 and 2021, the EHT cooperation organization has not stopped the pace of observation research. Moreover, the number of EHT stations continues to increase. In 2018, three new stations were added, including the Greenland Telescope, and the coverage of the observation array was further expanded.

In future plans, more telescopes will be used to expand the EHT observation array.

In addition to the increase in the number of telescopes, starting in 2023, the EHT will conduct observations in the 0.87mm band, which will improve the resolution by nearly 50% compared to observations in the 1.3mm band under the same circumstances. Sagittarius A * and M87 * remain the most important scientific targets of the EHT collaboration, and astronomers are exploring how they change over time and studying the surrounding magnetic field.

The continued expansion of the EHT population and technological innovation will allow scientists to share more compelling astronomical photos, and even "movies" of black holes.

"Using the next-generation EHT to film such a’movie ‘of the black hole at the center of the Milky Way is the pursuit of astronomers." Some astronomers said so.

Scientists in our country have long been concerned about high-resolution black hole imaging research. In this EHT cooperation, scientists in our country actively participated in the joint promotion of early EHT international cooperation, the joint application of EHT observation time, the observation operation of the Maxwell Telescope in Hawaii, and the post-data processing and analysis.

Scientists will also aim their telescopes at other sources to make more "doughnuts," experts say, a goal that could be achieved by building space telescopes because other "doughnuts" are smaller. (Wang Ludan, Hebei Daily reporter)

Is the content suspected of violating the rules? The little red book was suddenly removed from the shelf, and there has been controversy in the past five months.

  Zhongxin Jingwei Client July 30th (Chang Tao) "Little Red Book ‘ Water inverse ’ Haven’t left yet. " On the morning of 30th, after seeing the news that "Little Red Book was suspected to have been removed from the shelves by major Android app stores" posted on Weibo Hot Search, senior user Xiaoyu (pseudonym) quipped in the comment area.

  The Sino-Singapore Jingwei client search found that as of press time, the Little Red Book App could not be downloaded and installed in the Android mobile app mall including Huawei, vivo, OPPO, Yijia and Xiaomi, and the Android mobile phone management software pea pods, Kuan and AppBao. However, the Apple App Store can still search for Little Red Books and download them normally.

  Little Red Book has been controversial in the past five months since it was exposed that "planting grass" notes were written and data was falsified on the eve of 315 this year. According to the ranking of complaints in the first half of 2019 published by Shanghai Consumer Protection Committee on the 29th, the number of complaints from Xiaohongshu exceeded 1,000, ranking in the top ten.

  Being removed from the platform by multiple platforms, the official response is "communicating"

  Zhongxin Jingwei noticed that when searching for "Little Red Book" in the app stores of vivo, OPPO and Xiaomi, the page showed "internal optimization, download is not available for the time being", while in Huawei’s app store, it showed "service adjustment".

  On the morning of the 30 th, the relevant person in charge of Xiaohongshu responded to the media that the product was suspected to be removed from the shelf. The company has learned about the situation and is actively communicating with relevant departments to solve it. Users who have installed Xiaohongshu App will not be affected in normal use.

  In fact, the sudden removal of products from the shelves is not "exclusive" to Xiaohongshu, which has happened to apps such as bilibili and Netease Cloud Music before.

  In July, 2018, bilibili was suspected of being taken off the shelves by some application stores, and it was later confirmed that eight video applications, including bilibili and Second Shot, were required to be taken off the shelves for one month in the centralized rectification action of the short video industry on the Internet. Since then, bilibili officials have issued a "comprehensive content rectification" announcement, saying that the content of the whole station will be rectified in strict accordance with the requirements, and the construction of the website audit team will be strengthened, and users will be mobilized to conduct self-examination and self-cleaning on the content and community.

  On June 29th, Netease Cloud Music, Himalayan and other online audio applications were removed from major app stores. On July 28th, Netease Cloud Music resumed its shelves in the Apple App Store.

  Some analysts believe that the reason why Xiaohongshu was removed from the shelves this time may be similar to that of bilibili and Netease Cloud Music: the content was suspected of violating the rules and should be removed for rectification at the request of the regulatory authorities.

  Controversial 5 months: note fraud, tobacco advertising, selling illegal drugs.

  According to the data, Xiaohongshu was established in 2013. It is the mainstream "content+e-commerce" platform at present, and it is also a "planting artifact" for many young consumers. Xiaohongshu officially disclosed that it has 250 million users and 85 million monthly activities. According to TheInformation, Xiaohongshu is currently negotiating financing of up to 500 million US dollars, and its valuation may reach 6 billion US dollars.

  Xiaohongshu has attracted much attention due to its rapid growth in the past two years, but at the same time, various chaos has quietly bred in the platform. Especially since March this year, Xiaohongshu has been in dispute.

  On the eve of 315 this year, the Sino-Singapore Jingwei client reported the "Little Red Book Planting Grass Notes Industry Chain". The survey found that the notes that made consumers crazy about "planting grass" on the Little Red Book platform may not come from the personal experience of real users, but were "fabricated" by professional writers according to the needs of businesses.

  In April, according to media reports, more than 90,000 tobacco soft articles appeared on the platform of Little Red Book. Later, Xiaohongshu announced that all the notes referring to tobacco were offline.

  In May, Xiaohongshu pointed the gun at the platform KOL (Key Opinion Leader): bloggers with less than 5,000 fans and less than 10,000 average notes in the past month will be disqualified as brand partners, and they will not be able to receive advertisements on the platform. According to media reports, under the new regulations, about one-third of the little red books KOL are affected.

  However, the survey of Sino-Singapore Jingwei client found that in less than a week after Xiaohongshu released this new regulation, a third-party brushing agency said that they could help KOL who failed to meet the standard to increase the exposure of notes and increase the number of fans. At the same time, some advertising public relations and brushing agency personnel also revealed that after the platform raised the entry threshold for brand partners, some Kols that met the standards started to sit on the ground and raised their own cooperation prices.

  Subsequently, Xiaohongshu began to strengthen the user evaluation system. On May 27th, Xiaohongshu announced the launch of the "Little Red Heart" scoring system, introducing the "one person, one vote" scoring mechanism, and all the scores were anonymous.

  Some insiders analyzed that Xiaohongshu’s adjustment is to save the trust crisis of the platform on the one hand, and pave the way for further commercialization on the other hand.

  In fact, in addition to e-commerce, on the road of commercialization, Xiaohongshu continues to explore. In June this year, Xiaohongshu requested to sign the Detailed Rules for the Management of Xiaohongshu Cooperative Organizations with MCN (a business model that produces professional content through online celebrity’s economic operation), one of which required the resident organizations to pay a deposit of 200,000 yuan. Subsequently, this clause raised questions.

  On July 27th, according to the Southern Metropolis Daily, there were still some illegal phenomena in Xiaohongshu App, such as Wechat business openly posting and displaying the sale of prohibited drugs in the country, recommending drainage to offline unqualified medical institutions and visiting doctors in the name of "planting grass", and even taking a lot of notes on the training course of "Amway" learning micro-plastic surgery on the 5th.

  In addition, the Zhongxin Jingwei client combed and found that in July, Xiaohongshu was successively named by the regulatory authorities.

  On July 2nd, WeChat official account, the official WeChat of the Ministry of Industry and Information Technology, reported the telecom service quality in the first quarter of this year. According to the report, the operating entity of Xiaohongshu, Hangyin Information Technology (Shanghai) Co., Ltd. (hereinafter referred to as "Hangyin Information Technology") has two problems involving users’ personal information, namely, collecting personal information without users’ consent and misleading users to agree to collect and use personal information. The Ministry of Industry and Information Technology said that it had ordered relevant enterprises, including Hangyin Information Technology, to rectify. (Zhongxin Jingwei APP)

The Great Wall Gun 6×6 will make its world debut at Shanghai Auto Show, with 3 axes, 6 drives and 5 locks.

A few days ago, pickup truck city learned from the Great Wall official that,China’s first 6X6 super off-road platform built by Great Wall Motor will be the world’s first show at the Shanghai Auto Show, which opened on April 18th this year, creating a brand-new category and leading China’s hard-core off-road to the next level. The first application of the Great Wall 6X6 super off-road platform technology will be the Great Wall Gun.The first "3-axis, 6-drive and 5-lock" in China has achieved the super off-road capability in all scenes and all terrain, and can realize the infinite expansion of the whole ecology.

The 6×6 platform of the Great Wall Gun will be the world's first show at the Shanghai Auto Show with 3 axes, 6 drives and 5 locks-Figure 1

At present, more specific information about the 6×6 version of the Great Wall Gun is unknown for the time being. According to the product planning information previously exposed, the new car willContinuing the chassis structure of front independent suspension with front double wishbone and rear multi-link integral bridge for the ordinary version of Great Wall Gun, the newly developed through middle bridge can bring longer suspension stroke and enhance off-road performance. Six-wheel-drive pickup truck has a longer vehicle size due to the addition of a rear axle, and the container can carry larger items, but it also tests the vehicle length control ability. If it exceeds 6 meters, it needs to hang a yellow motor vehicle number plate.

In terms of power, according to the common reference of six-wheel drive pickup trucks around the world, guessThe 6×6 version of Great Wall Gun is likely to adopt the top 3.0T V6+9AT combination of Great Wall Motor, with a maximum power of 260kW and a peak torque of 500N·m, providing consumers with stronger performance guarantee.

The 6×6 platform of the Great Wall Gun will be unveiled at the Shanghai Auto Show in the world with 3 axes, 6 drives and 5 locks-Figure 2

Six-wheel drive off-road pickup trucks are ceiling-level products all over the world, among which the most famous ones are modified models such as Mercedes-Benz G63 AMG 6×6, Hennessy Ram TRX Mammoth and Hennessy Veloci Raptor, which have conquered countless off-road enthusiasts with the off the charts performance of three-axle six-wheel drive+thousand horsepower+five locks.

Compared with the traditional four-wheel drive chassis, the chassis of six-wheel drive pickup truck has stronger stability and bearing capacity due to the design of double rear axles. Compared with heavy and medium-sized trucks, it has the characteristics of flexibility and maneuverability, which is more advantageous for RV modification, cross-country crossing and special vehicle building, and is very suitable for product development in the civilian market. Therefore, the appearance of the 6×6 version of Great Wall Gun will be a historic progress of domestic pickup trucks.

LI apologized.

Recently, a blogger called the LI test car "a farewell car in violation of regulations". It is understood that the driver of the test vehicle is an employee of Qingdao Yuzhe Automobile Engineering Technology Co., Ltd. (hereinafter referred to as "Qingdao Yuzhe"). On December 4th, LI official Weibo apologized for the traffic safety hazards caused by uncivilized driving behavior, saying that he had reiterated the importance and seriousness of observing traffic laws and regulations to all road test engineers and related suppliers.

The video footage released by the blogger.

It is understood that in the early morning of December 4, a blogger posted that an ideal MEGA test vehicle changed lanes to block a normal driving vehicle, and three people in the blocked vehicle were friends of the blogger. At the same time, the blogger released relevant videos, and the incident immediately triggered a heated discussion.

On the 4th, Qingdao Yuzhe issued an apology statement, claiming that the driver of the company, Liu, had behaviors that endangered road traffic safety when driving a test car in Shenzhen, and the company had asked the driver to deal with traffic violations at the first time. Qingdao Yuzhe said that the company apologized for the driver’s serious violation of traffic regulations and the negative impact it caused to the manufacturer. The company will dismiss the employee Liu involved.

On the same day, LI forwarded Qingdao Yuzhe’s explanation and apologized for it. LI said that he was deeply sorry for the traffic safety hazards caused by drivers’ uncivilized driving behavior. LI has reiterated the importance and seriousness of observing traffic laws and regulations to all road test engineers and related suppliers.

On the afternoon of the 4th, the blogger responded to the above apology, saying that his friend as a party accepted the apology and tested the driver’s traffic violations, and the traffic police were investigating further.

Original title: "LI Apologizes"

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20.98-29.98 million yuan, 2023 BYD Han EV Champion Edition car went on the market.

On March 16th, BYD held the Super Press Conference of Han and Tang Flagships today, and officially released the 2023 Han EV Champion Edition.The price range is 209,800-299,800 yuan..

IT House with 2023 BYD Han EV Champion Edition Price of each model:

In terms of design, the 2023 Chinese EV Champion Edition adopts the "Dragon Face" design language, with Chinese tail lights.Add Glacier Blue Car Paint Color Matching.

In terms of configuration, the new car is equipped with a 15.6-inch adaptive rotating Pad, which supports NFC car keys, wireless charging of mobile phones, high-efficiency heat pump air conditioning in a wide temperature range, and independent partition atmosphere lights.

In terms of power, the 2023 Chinese EV Champion EditionSingle motor and dual motor versions are available.. Among them, the single motor model has three power versions:

In addition, dual-motor modelsThe maximum power of the system is 380 kW and the combined torque is 700 Nm.The maximum power of the front motor is 180 kW and the peak torque is 350 Nm, and the maximum power of the rear motor is 200 kW and the peak torque is 350 Nm.CLTC cruising range 610km.

Chassis, Han EV Champion EditionEquipped with front McPherson+rear multi-link independent suspensionFSD variable damping suspension is standard for front-wheel drive vehicles, DiSus-C intelligent electronically controlled active suspension is equipped for four-wheel drive vehicles, and the suspension arm and steering knuckle are made of materials.Change from iron material to aluminum alloy material.

Genxi Bio will announce the latest research results of BCMA/CD19 dual-target CAR-T cell therapy GC012F based on FasTCAR platform in the treatment of relapsed/refractory multiple myeloma at ASCO Annual

Suzhou, China, Palo Alto, California, USA May 20, 2021/PRNewswire/-Genxi Biotechnology Group (NASDAQ: GRCL;; Genxi Bio, a global clinical biopharmaceutical company dedicated to developing efficient and economical cell therapy for cancer treatment, announced today that it will publish the latest clinical research results of a multi-center, first-time human trial on GC012F in the treatment of relapsed/refractory multiple myeloma during the annual meeting of American Society of Clinical Oncology (ASCO) in 2021 and the conference of European Hematology Association (EHA) in 2021.

GC012F is a BCMA/CD19 dual-target autologous CAR-T cell therapy developed based on the patented technology platform of Genxi Bio-FasTCAR, which has the advantage of "production can be completed the next day". At present, the candidate product is being evaluated in a phase I clinical trial initiated by researchers.

  • By January 12, 2021, 19 patients with multiple myeloma were enrolled in the three dose groups of this study, of which the highest dose level was 3×10.fiveCells/kg body weight, all the above patients meet the criteria of recurrence/refractory after multiple rounds of treatment. Subsequent patients (after the release of data at the ASH annual meeting in 2020) received the highest dose level of treatment.
  • The early objective remission rate (ORR) was as high as 94.7%(18/19), and all the responses showed that excellent partial remission (VGPR) and even complete remission (SCR) were obtained. The data of all dose groups showed a rapid, in-depth and lasting therapeutic effect.
  • All patients (n=9) who received treatment in the highest dose group achieved negative minimal residual lesions-complete remission (MRD- sCR) in a strict sense.
  • Of the 19 patients, 18 (94.7%) belonged to the high-risk patients defined in mSMART 3.0 guidelines, and the median number of previous treatment lines was 5.
  • 94.7%(18/19) patients have been exposed to PI, IMiD and at least the third treatment scheme, including anti-CD38 targeted therapy.
  • The safety of GC012F is consistent with the previous observation results, and the main symptom is low-grade cytokine release syndrome (CRS)(84% patients are grade 1/2; 11% (n=2) patients were grade 3), and there was no grade 4 or 5 CRS;. No immune effector cell-related neurotoxicity (ICANS) was observed in 19 patients. Adverse events (TEAEs) occurred during treatment were mainly manifested as decrease of blood cell count and increase of AST. All TEAEs were relieved after standard treatment.
  • The study will continue to evaluate the effectiveness and safety of GC012F in the treatment of patients.

"I am glad to see the mutual evidence between the follow-up of the initial patients and the treatment effect of the subsequent patients, which not only confirms the research results announced at the annual meeting of ASH last year, but also further clarifies the excellent safety and effectiveness of GC012F dual-targeted autologous CAR-T cell therapy, including for high-risk patients."Chief Medical Officer of Genxi BiologydoctorIt said: "High-risk patients are usually extremely difficult to treat, but all patients in the highest dose group in this study have reached the MRD negative sCR state and maintained a deep response for six months or even longer after receiving GC012F infusion. The above exciting research data bring brand-new hope to high-risk patients (including those who do not respond to the standard treatment plan). Next, we plan to promote this research on a global scale, including promoting it as a more preferred treatment option. I look forward to sharing more developments with you in the near future. "

GC012FClinical research initiated by researchers (IIT) Co-principal researcher, Professor Du Fu of shanghai changzheng hospital."Multiple myeloma (MM) is a malignant blood tumor that is extremely difficult to treat. There are about 750,000 patients with multiple myeloma worldwide.[1]There are about 160,000 new patients every year.[2]And it is on the rise year by year. Among them, high-risk patients account for 20%-30%.[3]The prognosis is usually poor, accompanied by higher risk of early recurrence, shorter progression-free survival and overall survival. This time, we are pleased to see that the BCMA/CD19 dual-target autologous CAR-T cell therapy GC012F of Genxi Bio has shown excellent effectiveness and safety for the long-term follow-up results of patients with relapsed/refractory multiple myeloma. And thanks to the advantages of FasTCAR platform, the waiting time of clinical treatment has been significantly shortened, and the hope of life has been ignited for more patients. "

GC012FClinical research initiated by researchers (IIT) Co-principal researcher, Professor Fu Weijun of shanghai changzheng hospital.Said: "I am very happy to see that after we announced the first human trial data of GC012F in the form of oral report at the ASH meeting last year, this research has made positive progress again, and the previous results have been further verified; This also allows us to see the good application prospects of Ganxi Bio-FasTCAR platform and Dual CAR technology. With the deepening of research, the clinical benefits of this innovative BCMA/CD19 dual-targeted autologous CAR-T cell therapy for patients with multiple myeloma, especially high-risk patients, are constantly emerging. It is expected that this research will continue to achieve more results and strive to meet the urgent treatment needs of patients with recurrent/refractory multiple myeloma as soon as possible. "

Details of the electronic poster are as follows:

2021American Society of Clinical Oncology (ASCO) annual meeting

abstract8014Long-term follow-up results of the first multicenter human trial of BCMA/CD19 dual-target CAR-T cell therapy GC012F for patients with relapsed or refractory multiple myeloma based on FasTCAR platform.

Poster release date:June 4, 2021

2021European hematology association (EHA2021) conference

abstractEP962Long-term follow-up results of the first multicenter human trial of BCMA/CD19 dual-target CAR-T cell therapy GC012F for patients with relapsed or refractory multiple myeloma based on FasTCAR platform.

Poster release date:June 11th, 2021

About multiple myeloma

Multiple myeloma (MM) is the third most common malignant hematological tumor in the United States. Its tumor cells originated from bone marrow plasma cells, an immune cell responsible for secreting anti-infective antibodies. About 160,000 patients worldwide are diagnosed with multiple myeloma every year; In 2020, the United States is expected to have more than 32,000 confirmed patients. In recent years, although many progress has been made in the treatment of multiple myeloma, the clinical treatment effect is still unsatisfactory. International Myeloma Working Group (IMWG) and the consensus guidelines of Mayo ST Rating for Myeloma and Risk-Adapted Therapy (MSMART) classify patients with specific cytogenetic abnormalities or other abnormalities as high-risk patients, and this group accounts for 20-30% of all patients with multiple myeloma. High-risk patients with high risk of early recurrence, progression-free survival and short overall survival are considered as the most difficult patients with multiple myeloma, and usually have poor prognosis.

aboutGC012F

GC012F is a candidate product for dual-target autologous CAR-T therapy based on FasTCAR platform. At present, the candidate product is evaluating its safety and effectiveness in the treatment of multiple myeloma in a multi-center and phase I clinical trial initiated by researchers, covering many research centers in China. GC012F brings rapid, in-depth and lasting therapeutic effects to patients with multiple myeloma by simultaneously targeting the malignant plasma cell site expressing BCMA and the early progenitor cell site expressing CD19. 

aboutFasTCAR

FasTCAR is a technology platform with intellectual property rights of Genxi Bio, aiming at developing high-quality autologous CAR-T cell therapy. Preclinical studies show that the phenotype of CAR-T cells produced by FasTCAR technology platform is younger, the degree of depletion is lower, and the amplification ability, persistence, bone marrow migration ability and tumor cell clearance activity are enhanced. With the advantage of "completing production the next day", FasTCAR platform technology can greatly improve cell production efficiency, thus significantly reducing production costs and enabling cell therapy to benefit more cancer patients.

About genxi creatures

Genxi Biotechnology Group (Genxi Bio for short) is a global clinical biopharmaceutical company dedicated to the discovery and development of breakthrough cell therapy. Using its pioneering FasTCAR and TruUCAR technology platforms, Genxi Bio is developing a number of rich clinical cancer treatment product pipelines, both autologous and allogeneic. These products are expected to overcome the persistent major industry challenges of traditional CAR-T therapy, including long production time, poor production quality, high treatment cost and lack of effective treatment for solid tumors. To learn more about Genxi Bio, please visit www.gracellbio.com/ Concern LinkedIn account @GracellBio.

Warning statement about forward-looking statements

The statement in the press release about future expectations, plans, prospects and other non-historical facts may contain a "forward-looking statement" as defined in the Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements related to the expected transaction and completion time of this offering. These statements may, but do not necessarily, contain the following words and corresponding negative forms or similar words: purpose, expectation, belief, estimation, prediction, plan, possibility, prospect, plan, potential, conjecture, formulation, seeking, possibility, should and will. Due to various important factors, the actual results may be significantly different from the forward-looking statements, and there is no guarantee that any forward-looking statements will be realized. These important factors include the factors mentioned in the Risk Factors section of Genxi Bio’s recent annual report in Form 20-F, and the discussion on potential risks, uncertainties and other important factors in Genxi Bio’s subsequent report to the US Securities Regulatory Commission after the session. Any forward-looking statements in this statement only reflect the current expectations, and Genxi Bio has no responsibility to publicly update or review any forward-looking statements, whether based on new information, future events or other reasons. Readers are requested not to rely on forward-looking statements after the publication date of this press release.

Media contact


marvin.tang@gracellbio.com

Investor contact

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