With the development of Internet and self-media, the spread of rumors is accelerating. In the process of preventing and controlling the epidemic in COVID-19, various rumors emerged one after another, which had a great impact on social order.

　　Recently, wenjuan.com, the Social Investigation Center of China Youth Newspaper, conducted a survey on 2003 respondents, showing that 66.2% of the respondents admitted that they had been recruited by rumors. 73.5% of the respondents believe that rumors will disrupt social order. 69.0% of the respondents suggested establishing a rumor system to update the rumor information in time.

　　Among the respondents, 4.2% were born after 00, 28.9% after 90, 46.9% after 80, 15.3% after 70 and 4.1% after 60. Men account for 44.1% and women account for 55.9%.

　　66.2% of respondents admitted that they had been recruited by rumors.

　　Liu Wen (pseudonym), 27, works in Tianjin. During this time, she saw many so-called ways to prevent COVID-19, such as gargling with salt water, drinking alcohol and smoking vinegar, and many of them were later identified as rumors. "Some rumors can be judged according to common sense, while others need more information to distinguish them."

　　Liu Wen said that with the development and changes of the epidemic, she recently noticed some rumors about the epidemic cases, "for example, where there are clustered cases, or where there are cases in the area where she lives." However, I usually take the official information as the standard. "

　　In the survey, 66.2% of the respondents admitted that they had been recruited by rumors. 14.0% of the respondents feel that they have a strong ability to identify rumors, 63.2% feel strong, 22.1% feel not strong, and 0.8% of the respondents frankly have no.

　　Yang Binyan, an associate researcher at the Institute of Journalism and Communication of China Academy of Social Sciences, said that at present, people’s demand for information has increased dramatically, and they will constantly check and collect relevant information. Because of the worries and fears about the epidemic, people are more likely to believe rumors. In addition, in the era of mass communication, sudden emergencies have greatly aroused the information exchange and communication behavior of ordinary people and various subjects. "The amount of information is huge, and the subjects of voice are diverse, so people often feel that the information is difficult to distinguish between true and false".

　　69.0% of the respondents suggested establishing a rumor system to update the rumor information in time.

　　"Rumors like a ‘ Information virus ’ People who lack the ability to distinguish may be recruited. Rumors may also have a diffusion effect and must be blocked in time. " Tian Rui, a post-95 girl who lives in Beijing, said.

　　Regarding the possible impact of rumors, in the survey, 73.5% of the respondents thought it would disrupt social order, 68.4% thought it would spread negative emotions and 63.7% thought it would aggravate social panic.

　　"Although said ‘ Spread rumors, open your mouth and break your leg ’ However, if the rumor information is not spread in time, it will only increase the harm of rumors. " Tian Rui feels that it is very important to dispel rumors and block the spread of rumors in time.

　　To reduce the harm of rumors, 69.0% of the respondents suggested to establish a rumor system and update the rumor information in time, 66.8% suggested to improve the public’s media literacy and ability to identify rumors, 65.1% suggested to release authoritative news in time to let the truth run through rumors, and 54.5% suggested to increase the punishment for rumors and increase the illegal cost.

　　"The public opinion survey laboratory of China Academy of Social Sciences conducted a survey during the epidemic and came to the conclusion, ‘ The traditional mainstream media is the ballast stone of information dissemination and public opinion during the epidemic ’ 。” Yang Binyan believes that in the face of sudden public health incidents, it is the top priority of the media to conduct public communication quickly, timely, accurately, truly and scientifically, and it is the first responsibility that the media needs to bear in an emergency. The traditional mainstream media is duty-bound to undertake such tasks and missions. Under the epidemic situation, the public’s demand for news information has greatly increased, which requires orderly organization and coordination and continuous professional content production, and the advantages of traditional mainstream media are outstanding.

　　How do ordinary people deal with rumors? Yang Binyan believes that the ability to identify rumors can be improved from the following aspects: first, we should pay attention to the sources of information and obtain information from authoritative scientific information sources, such as the authoritative release of central media and central and local governments; Second, under the theme of "fighting pneumonia", some platforms have a column dedicated to "dispelling rumors", which can be used for more reference; Thirdly, it is necessary to see clearly what news is released by news media and what are the opinions and comments of netizens, including experts, celebrities, big V, online celebrity and so on, and to distinguish between "news" and "opinions".

　　Zhongqingbao Zhongqingwang reporter Sun Shan Source: China Youth Daily

　　Yantai Development Zone Senior Middle School held the ceremony of campus youth adulthood. Photo courtesy of Yantai Education Bureau

　　editorial comment/note

　　In the process of educational reform and development, many typical models have emerged. They have had an important influence and made important contributions in the history of new China’s education development. For many years, they have also been persistent in the journey of educational reform. In order to present these typical new achievements and experiences in further promoting education reform, starting from today, this newspaper will open the column of "70 Years of Magnificence and Typical Return Visit in the New Era of Struggle", and successively publish the typical return visit reports that have been launched by this newspaper, so please pay attention.

　　Quality education is an unavoidable topic in contemporary China education. From the early days of reform and opening up, many places have begun to explore hard. In this exploration, Yantai is another unavoidable place.

　　In 1984, the first experimental area of educational reform in China was born in Yantai. In 1990, the State Education Commission identified Yantai as a pilot city for comprehensive urban education reform in China. In 1992, Yantai’s experience in quality education reform attracted much attention, and People’s Daily and China Education News reported it one after another. In September 1997, the national experience exchange meeting of quality education in primary and secondary schools was held in Yantai, which became an advanced model of quality education in China.

　　In the development history of quality education, the pace of Yantai people’s reform has never stopped. For more than 30 years, they have unswervingly implemented quality education and written a rich and colorful stroke.

　　Recently, our reporter went deep into Yantai, Shandong Province for investigation and interview, revisited the forefront and fiery scene of the reform in that year, and analyzed the latest progress of quality education reform, with a view to providing a reference model for the latecomers who promote quality education today with Yantai, the "living fossil" of quality education.

　　From the individual to the whole — —

　　Always take the growth of students as the foundation.

　　Qu Wenteng, a chemistry teacher at Dayao Middle School in Muping District, is very happy in recent years. Because of the appearance of the tutorial case, a teaching pain point that has plagued him for many years has been solved at once: the problem of uneven students’ level — — Some people don’t have enough to eat, and some people can’t eat.

　　The guiding plan adheres to the design principle of few, precise and thoughtful. By designing hierarchical learning objectives, leading questions and corresponding exercises, students with different learning situations can be guided to find their own content and methods. This efficient classroom reform with the guidance plan as the core has been carried out in Dayao Middle School for more than ten years. President Sui Zhengong said that this model is based on respecting students’ differences, aiming at developing students’ differences and cultivating students’ self-learning ability, and its core is student-oriented.

　　Speaking of the concept of differentiated teaching, Sui Zhengong said that this is actually in line with the junior high school quality education reform implemented by Dayao Middle School more than 30 years ago.

　　Back in the 1980s, in order to consolidate the achievements of "Nine-Year General Education" and better implement quality education in junior high schools, Yantai City, starting from the goal of all-round development, lost no time in launching the overall reform plan of "two-for-all, two-for-four reform" with classified guidance and separate teaching as the main ways, with 16 different types of junior high schools such as Dayao Middle School in Muping District, Beima Middle School in Longkou City and Qixia Experimental Middle School taking the lead in "classified guidance".

　　Dayao Middle School at that time was the pioneer of reform. Under the leadership of Li Peizhi, then principal of the school, the school explored and built a junior high school education model of "two parts", which was praised as "the golden key to open junior high school quality education". Subsequently, Dayao Middle School was recognized as "an advanced model of quality education in primary and secondary schools in China" by the State Education Commission and relevant experts. In September 1997, the State Education Commission held a national experience exchange meeting on quality education in primary and secondary schools in Yantai, and Dayao Middle School was selected as a "junior high school" to visit the site.

　　From the individual to the whole, this question, which was once placed in front of Li Peizhi and Sui Zhengong, got a similar answer in line with the spirit of the times under the concept of differentiated teaching.

　　More than 30 years have passed, and the research on differential education has never stopped in Yantai. The research on differential education has become an excellent research project that regional professional researchers and front-line principals and teachers have participated in and adhered to for 23 years. More than 1,000 experimental teachers from 212 experimental schools have participated in the project experiment. The research achievement won the second prize of provincial basic education teaching achievement twice in a row.

　　Focusing on the all-round development of students, the student-oriented curriculum reform is being continuously and comprehensively promoted in Yantai. At present, differentiated teaching has been extended to all disciplines and all aspects of school work, and different students have obtained development paths suitable for their own growth here.

　　From result to process — —

　　Always take evaluation reform as the guide.

　　Sports and art are a happy thing in Laizhou bilingual school. This is the goal that President Zhao Fuqing has been pursuing for many years. "I just want to make sports and art change from passive to conscious, from task to interest, and from result to process."

　　In order to achieve this goal, the school has set up a set of evaluation system of physical arts based on process evaluation, such as classroom observers, nine-day sports meeting, home sports homework, sports cooperation teaching, and the evaluation scheme of "physical fitness+skills" & HELIP; …

　　The sports meeting of Laizhou Bilingual School lasts for 9 days, from class to department and then to the whole school. Everyone is an athlete and everyone can get evaluation. During holidays, with the participation of parents, students have to complete a physical exercise every day; In the classroom, evaluation is divided into teacher evaluation and student evaluation, and student evaluation evaluates and summarizes the performance of each group by classroom observers in each class … …

　　Zhao Fuqing, who has been teaching for many years, has participated in and experienced the quality education reform in Yantai for many years. In his view, Yantai’s sports and arts reform comes down in one continuous line.

　　After the resumption of the college entrance examination in 1977, Yantai’s enrollment rate has been among the best in Shandong Province, and people used to be proud of it. Later, in order to pursue the enrollment rate, some schools began to take further studies as the baton and cut off the courses of music, physical education and beauty.

　　The reform of quality education in Yantai begins with the reform of examination system and evaluation system. First of all, the reform of the 100-point system was abolished in primary schools, and the evaluation method of "grade+specialty+comment" was implemented to liberate primary school students from the weight of scores. All subjects in primary schools are assessed by sub-items, and rated according to four grades: excellent, good, passing and failing. The assessment will be carried out by combining the daily examination with the comprehensive examination.

　　Looking back on the past, how similar this is. Since 2012, Yantai Education Bureau has studied and put forward the idea of school physical education reform of "scientific research leading, administrative promotion, point-to-area and regional promotion", taking the lead in establishing the development concept of "healthy sports, scientific sports and all-round sports" in the country. After more than six years of exploration and practice, the city’s education system has gradually established a five-in-one school physical education reform system of "complete guarantee, curriculum optimization, training promotion, competition guidance and standard guidance", laying a solid foundation for students’ lifelong physical education.

　　From the baton focusing on results to the evaluation system focusing on process, Yantai quality education has blossomed in various campuses. On the campus of Penglai No.2 Experimental Primary School, the hall of the teaching building has become a stage for students to display, and the most conspicuous wall is reserved for the "one-star" students who perform best every month. Even the piano in the corner has become a stage for students to compete for display, and the campus is full of students’ cheers and smiling faces. At the Second Experimental Primary School in Muping District, every day at noon, the reading forum starts on time and persists every day, rain or shine. This normalized speech activity has cultivated students’ confidence and ability to speak and express in front of everyone.

　　From school to society — —

　　Always aim at all-round development.

　　For students living in Yantai, social practice is a necessary action to participate in and complete with their parents.

　　Since the summer of 2013, Yantai has organized and guided students and parents to participate in the social practice activities of "practice base group, social big classroom" in the city by means of "parents’ full participation and timely guidance from the school", and entered social venues such as museums, nuclear power plants and air forces that are open to primary and secondary school students free of charge.

　　After more than six years, Yantai has gradually established a comprehensive practical activity curriculum system with the theme of "ideal moral construction, vocational skills training, scientific exploration and innovation, and comprehensive quality improvement" and the characteristics of "school+base group". Up to now, Yantai has built 33 municipal social practice listing bases, 139 county-level listing bases and 560 school-level listing bases, and the characteristic practice education base group of primary and secondary schools has begun to take shape.

　　The comprehensive practical curriculum system in full swing is just one of the two wings of the new regional integrated moral education curriculum system that Yantai has continuously promoted in recent years. On the whole, Yantai’s framework is a new framework of "one subject and two wings" regional integrated moral education curriculum, which focuses on subject moral education curriculum and takes traditional culture curriculum and practical activity curriculum as two wings.

　　"The outstanding feature of the new system of Yantai regional integration moral education curriculum is three combinations." Xu Jianmin, director of Yantai Education Bureau, introduced that the combination of administrative decision-making and scientific research guidance, inheritance and innovation and development, and school, family and social education should be adhered to.

　　Since it was established as a national experimental area for educational reform in 1984, Yantai has made rich experience and achievements in the field of moral education reform in primary and secondary schools while deepening the reform of quality education. On the one hand, Yantai organically integrates the scattered experience of a single point, and then grasps the point and gives full play to the role of demonstration radiation; On the other hand, based on the new situation and requirements of moral education and the new situation and problems of school moral education reform and development, the classic educational wisdom is organically integrated into the brand-new moral education practice.

　　After three years of exploration and practice, the reform and development of integrated moral education curriculum in Yantai city is in good condition. Five schools in the city have been rated as national excellent Chinese traditional culture demonstration schools, and the moral education courses of more than 130 schools have become gold medals in their respective districts and cities, becoming the "favorite" for school principals and teachers in the city and the region to watch and learn.

　　Walking into the second experimental primary school in Muping District, I was just catching up with an "apricot" thing at school: picking apricots. In the school’s "pocket garden" and dozens of apricot trees near the courtyard wall, golden and full apricots are ripe. The students excitedly and carefully picked the apricots they planted one by one.

　　President Jiang Yuemei introduced that in order to provide students with sufficient practice space and create opportunities for "working all the time", the school has carried out four aspects of work: developing "pocket vegetable garden" and building a labor platform; Scientific planting management to improve labor quality; Carry out research study to enhance labor skills; Take advantage of the charity sale and feel the meaning of labor. It is worth mentioning that according to the solar terms, the school compiled the school-based textbook "Follow the solar terms", and these "small farmers" followed the solar terms textbook to carry out inquiry learning and research.

　　In 2017, the integrated observation and exchange activities of moral education courses in primary and secondary schools in Shandong Province were held in Yantai, which was highly praised by the Provincial Department of Education and peers in the province. In 2018, the results of the integrated reform of Yantai moral education curriculum won the second prize of the provincial basic education teaching achievements.

　　From Method to Theory — —

　　Always guided by education and scientific research.

　　Under the observation and discussion of more than 600 people in two days, Yin Shaoping, the principal of Zhaoyuan Experimental Primary School, has a deeper and broader understanding of the "12xue internet plus Teaching Characteristic Model" that she insists on, and at the same time, she has strengthened her confidence in going on. In November 2018, the "Yantai Education and Scientific Research Tour" series of activities was held in Zhaoyuan, Yantai. More than 600 people from all the staff, principals of primary and secondary schools and key teachers of all counties and cities participated in the activities.

　　"This session is ‘ A trip to education and scientific research ’ The ninth stop. " Guan Xiji, Dean of Yantai Academy of Educational Sciences, said that this activity was started in 2010 in Yantai, and it entered a county every year. The number of participants exceeded 1,000 for many years. The content of the activity deepened year by year, and the coverage continued to expand. A large number of advanced units and outstanding teachers emerged with this platform, forming a core brand in the field of regional education and scientific research.

　　"Yantai’s quality education reform has always had an important principle — — Guided by scientific research. " Guan Xiji hit home.

　　Xu Jianmin put forward the basic requirements of "improving our work with research spirit, research thinking, research methods and research standards, taking research as a way of work and becoming the level of work we pursue", and "promoting educational research with administrative power and carrying out educational administration with research spirit".

　　It is under the guidance of research spirit that Yantai can break through the primary stage of finding solutions to practical problems and transform and refine various reforms into scientific tools and even theories in time. According to statistics, in 2016, the first outstanding achievements in educational science research in Shandong Province were selected, and Yantai ranked first in the province in terms of the number of awards, the passing rate and the fields involved; In 2017, the number, passing rate and categories involved in the annual project of the 13 th Five-Year Plan for Education Science in Shandong Province ranked first in the province; In 2018, the province’s basic education teaching achievement award passed the second place in the province; In 2019, the passing rate of basic education and teaching reform projects in Shandong Province once again ranked first in the province.

　　Thirty years of hard work. In the late 1980s, for a long time after the resumption of the college entrance examination, students, parents, schools and society were all pursuing the enrollment rate, and there were many calls for reform, and all localities explored ways to promote students’ all-round development. The quality education reform in Yantai is just the right time.

　　From "cancel the percentage system and implement ‘ Grade+specialty+comment ’ The evaluation method, liberating primary school students from the weight of scores ",to" implementing ‘ Classification guidance ’ , implemented in the graduation grade ‘ Diversion education ’ , don’t have to hordes to squeeze ‘ A wooden bridge ’ " Finally, to "reform the enrollment system of senior high school entrance examination, link the enrollment quota of senior high schools and technical secondary schools with the conditions and level of running schools in towns and villages, and turn the competition for further education into the competition for running schools" … …

　　In 1997, the national experience exchange meeting on quality education in primary and secondary schools was held in Yantai. The meeting not only summed up the experience, but also made a comprehensive plan and deployment for the implementation of quality education throughout the country. This marks that the reform of quality education in China has entered the stage of national reform from regional experiment.

　　Yantai contributed a lot.

　　Now, when you walk into Yantai, you will find that learning has become a happy and fulfilling thing. Students with comprehensive qualities have made great achievements in the college entrance examination and talented people have emerged in large numbers. Walking into Yantai, you will find that the implementation of quality education is no longer a slogan, but a real action by governments, schools and teachers at all levels; Walking into Yantai, you will find that the strategic vision and great courage of the pioneers of reform have been inherited in the same strain, and the motivation for reform has not diminished.

　　Yantai, always on the road … …

　　Our reporter Yan Yuekun Zhang Shenghua correspondent Lu Peng

　　Few things touch people’s hearts as much as health. Health care is the key to people’s livelihood.

　　More new drugs are on the market, "noble drugs" are included in the medical insurance drug list, the "healthy China" action plan is deepened, and the chaos of medical beauty is rectified with heavy blows … … In 2019, these medical and health events related to people’s livelihood attracted special attention. At the end of the year, people hope to further "improve quality" and "reduce prices", and expect relevant departments to prescribe more health "prescriptions" to continuously improve people’s sense of acquisition and happiness.

　　one

　　Responding to the challenge of drug resistance, Tu Youyou team clarified the mechanism of artemisinin drugs

　　Artemisinin is a gift from traditional Chinese medicine to the world, which has contributed to the global malaria control. However, in recent years, the underlying mechanism of artemisinin in the treatment of malaria is still unclear, especially the problem of drug resistance, which is also the biggest challenge facing the global malaria control.

　　The half-life of artemisinin in human body (the time required for drug concentration to drop by half) is very short, only 1-2 hours. The course of clinical recommended artemisinin combination therapy is 3 days, and the truly efficient insecticidal window of artemisinin is only limited to 4-8 hours. However, the existing drug-resistant insect strains make full use of the short half-life of artemisinin, change their life cycle or temporarily enter a dormant state to avoid the sensitive insecticidal period. At the same time, plasmodium can also produce obvious resistance to the auxiliary drug "antimalarial formula" in artemisinin combination therapy, which makes artemisinin combination therapy "ineffective".

　　On April 24th, Tu Youyou’s team published an article online in the top international medical journal "New England Journal of Medicine", saying that the recently clarified mechanism of artemisinin drugs shows that they are precursors activated by iron or heme. Iron and heme are by-products of hemoglobin digestion, reaching the highest concentration at the mature stage of plasmodium trophozoite. Once artemisinin drugs are activated, many protein and heme of parasites will be alkylated. Alkylation of heme can also inhibit the detoxification of heme. "It is speculated that the mutation of a single protein target is unlikely to cause drug resistance, which may also explain why artemisinin drugs are still effective after decades of widespread use." Wang Jigang, a member of Tu Youyou’s team and a researcher at Artemisinin Research Center of Chinese Academy of Traditional Chinese Medicine, said.

　　In this regard, the team proposed a new treatment response plan: First, appropriately extend the medication time; The second is to replace the adjuvant drugs that have developed resistance in artemisinin combination therapy.

　　2

　　Can the "white list" of medical beauty be cured?

　　Non-medical beauty places are engaged in medical beauty treatment, the practice of doctors with informal training, and the use of unqualified medical beauty products … … In recent years, the "three non-"chaos exposed by the media has repeatedly been criticized by the society.

　　On June 18th, the National Health and Wellness Committee indicated that China Plastic Surgery Association was studying and formulating a credit evaluation management system, and it was planned to conduct credit evaluation of beauty medical institutions in some areas on a pilot basis. "The data of hardware conditions and facilities, annual inspection and doctor qualification of medical beauty institutions will be connected with the existing credit system, and a medical beauty institution &lsquo will be established in the future; White list ’ , objectively present to the people ‘ White list ’ The situation of the organization. " Cao Dequan, deputy secretary-general of China Plastic Surgery Association and director of the evaluation office, said that at that time, the public can search for information on the special website.

　　Hu Jieren, an associate professor at Tongji University Law School, said that the system itself is highly scientific and operable. It can learn from the existing credit evaluation model, listen to social voices, list the characteristics of dishonesty, and ensure fair and strict punishment. At the same time, in addition to credit evaluation and other mechanisms, the governance of medical beauty chaos requires multi-dimensional efforts and the participation of the whole society. For example, the regulatory authorities should take the initiative and increase penalties.

　　three

　　The Healthy China Action Plan is issued. Everyone is the first person responsible for his own health.

　　In July, the "Healthy China Action Promotion Committee" established in the State Council released "Healthy China Action (2019— 2030), giving authoritative guidance on what to do, how to do it and who will take the lead in healthy China.

　　"Everyone is the first responsible person for his own health." Wang Xiaoning, director of the Institute of Geriatrics of the General Hospital of the People’s Liberation Army and secretary-general of the China Association for Science and Technology’s life science association, particularly agreed with this point in the document. He explained that WHO has already concluded that in the promotion and maintenance of national health, the contribution of medical care is less than 10%, which mainly depends on people’s lifestyle and living environment. Wang Xiaoning said: "It turned out that ‘ Grip ’ The focus is on the 10% part, and now it is necessary to put ‘ Grip ’ Put it in 90%, that is, people’s lifestyle and living environment. "

　　Experts say that it is not enough for doctors and health departments to embrace health. Cardiovascular and cerebrovascular diseases are the first cause of death among Chinese residents, "Healthy China Action (2019— In 2030), it is mentioned that the goal of healthy China will reduce the premature mortality rate of major chronic diseases from 18.5% in 2015 to no more than 15.9% in 2022. Yang Jingang, an associate professor at Fuwai Hospital of China Academy of Medical Sciences, believes that the goal can only be achieved by mobilizing social forces, and the organizational model of "Patriotic Health Campaign" can be used for reference. Only by linking disease prevention and control indicators with the performance and responsibility of district leaders can we coordinate all resources and really play a role.

　　four

　　Major projects support the initial establishment of a drug innovation technology system in China.

　　In view of the difficulties and expensive medical treatment for ordinary people, and the heavy dependence on imports of high-end medical equipment and drugs, as early as 2008, China deployed and implemented the major scientific and technological project of "major new drug creation" (hereinafter referred to as the new drug creation project).

　　"With the special support of new drug creation, a total of 14 Class 1 new drugs were approved after February 2017, showing a blowout growth." At the end of July, at the conference of "Creation of Major New Drugs", Chen Kaixian, deputy chief engineer of special technology and academician of Chinese Academy of Sciences, introduced that in the past two years, new progress has been made in the research and development of special varieties, and six Class I new drugs have been approved for the treatment of malignant tumors. In addition, the achievements of the special project of new drug creation include the first domestic and the second long-acting anti-AIDS drug, the new anti-infective drug, Clindamycin, which is independently developed, and the world’s first aromatic hydrocarbon receptor modulator and non-hormonal small molecule chemical drug, Benvimod & HELIP, which has therapeutic effect on psoriasis. …

　　The national drug innovation technology system has been initially established in the special project of new drug creation, and a series of technical platforms have been laid out; Initially, a grid-based innovation system with scientific research institutes and universities as the main source innovation, enterprises as the main technology innovation, the close integration of the upper, middle and lower reaches and the deep integration of politics and Industry-University-Research has been established, and the ability of independent innovation has been significantly improved.

　　five

　　The paper has sparked a heated discussion on whether "Aristolochic acid-induced liver cancer" is a real hammer or a misunderstanding.

　　In August, aristolochic acid once again became the focus. Han Zeguang, a professor at systems biomedicine Research Institute of Shanghai Jiaotong University, published a paper in the international journal Hepatology in the field of liver diseases, which was emphasized by many media as "aristolochic acid has caused liver cancer to have a real hammer". This study revealed that aristolochic acid alone can cause liver cancer in mice in a dose-dependent manner, that is, the greater the dose of aristolochic acid, the shorter the time to cause liver cancer and the larger the tumor. When aristolochic acid is combined with carbon tetrachloride, it can induce liver cancer in mice in a dose-dependent manner, including hepatocellular carcinoma and hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

　　However, Luan Yang, a researcher at Shanghai Jiaotong University School of Medicine, and others believe that the data obtained by Han Zeguang’s team under certain experimental conditions are not enough to draw the conclusion that aristolochic acid causes liver cancer, and it cannot be called a "real hammer". "Specific experimental conditions" means that the experimental object is young mice and carbon tetrachloride liver injury model.

　　Some experts also said that some media interpreted the latest experiment of Han Zeguang’s team as "solid hammer" evidence that aristolochic acid is the main cause of liver cancer in China, but it should be noted that the original literature is in young mice (equivalent to 1-mdash; 2-year-old baby) and carbon tetrachloride liver injury model, which is different from the clinical occurrence of liver cancer, and many independent studies have been published in the world for many years, but no results of liver cancer caused by aristolochic acid have been made in adult mice, so it is too early to think that aristolochic acid is the main cause of liver cancer in China.

　　six

　　The original research drug went to sea for the first time, and the national research anticancer drug was approved for listing in the United States.

　　A movie, Dying to Survive, made anticancer drugs attract public attention. Subsequently, zero tariffs on imported anticancer drugs and negotiations on anticancer drugs have also become hot spots of public concern.

　　On September 23rd, the National Health and Wellness Commission and other 10 departments jointly issued the Healthy China Action — — Cancer prevention and treatment implementation plan (2019— In 2022) (hereinafter referred to as the "Program"), the "Program" pointed out that a set of "combination boxing" will be made by unblocking the temporary import channels of anticancer drugs that are urgently needed in clinic, promoting the substitution of generic drugs, and incorporating them into medical insurance, so as to improve the accessibility of anticancer drugs and enable ordinary people to buy, afford and use anticancer drugs in China.

　　The "Proposal" clearly stipulates that the zero tariff on imported drugs should be promoted, and various links such as R&D, production, procurement, import and use should be fundamentally straightened out, and the price of anticancer drugs will continue to decline, further promoting the simultaneous listing of new overseas drugs in China and avoiding the "foreign moon and domestic circle" caused by the difficulty in obtaining anticancer drugs.

　　Nowadays, the situation of "only getting in but not getting out" of original anticancer drugs has been broken. On November 14th, zanubrutinib, a BTK inhibitor developed by Baekje Shenzhou Company, was approved by the US Food and Drug Administration (FDA) for the treatment of adult patients with mantle cell lymphoma who had received at least one therapy before. At this point, "the drug became the first new anti-cancer drug independently developed by local enterprises in China and approved for listing by the FDA, realizing the new drug originally developed by China ‘ Zero breakthrough ’ 。” Dr Wu Xiaobin, general manager and president of Baekje Shenzhou China, said.

　　seven

　　Supervision is imminent. E-cigarettes are as harmful as traditional cigarettes.

　　Some businesses advocate that e-cigarettes are less harmful to human body and can help smokers quit smoking. Self-adjusting taste, cleanliness and environmental protection, and convenient use have all become eye-catching labels of e-cigarettes.

　　"Generally speaking, e-cigarettes will highlight the characteristics of high technology content and trendy fashion in product performance and ingredients. However, the ingredients of e-cigarettes are nothing more than nicotine, water, spices, propylene glycol and glycerol. As for the principle, it is even simpler, just an electronic evaporation, and there is no technology content at all." Zhang Zhigang, a senior engineer of China Environmental Behavior Law Society, said.

　　More seriously, consumers don’t know that under normal use conditions, the concentrations of some metals (including lead, chromium and nickel) and formaldehyde in some e-cigarette aerosols are equal to or higher than those in traditional cigarettes, and these harmful substances are even higher than the content of second-hand smoke produced by traditional cigarettes. In addition, e-cigarettes will also produce some toxic substances that are not found in traditional cigarette smoke, such as glyoxal, which is flammable, toxic and irritating, and its vapor or fog will stimulate eyes, mucous membranes and upper respiratory tract.

　　With the United States, Japan, India and other countries banning e-cigarettes to varying degrees, the voice that China should legislate and supervise e-cigarettes as soon as possible is getting louder and louder. Hu Qingyuan, director of the National Tobacco Quality Supervision and Inspection Center, said: "Fortunately, we have already started to act." On November 1, the State Tobacco Monopoly Bureau and the State Administration of Market Supervision jointly issued the Notice on Further Protecting Minors from E-cigarettes, urging enterprises or individuals that produce and sell e-cigarettes to withdraw their e-cigarette advertisements published through the Internet, and the supervision of e-cigarettes is becoming increasingly strict.

　　eight

　　Can cerebral palsy be cured? "Needle-sealing therapy" triggered a normative discussion on new therapy.

　　Cerebral palsy is recognized by the medical community as incurable. However, the media reported that the Third Affiliated Hospital of Zhengzhou University (hereinafter referred to as the Third Affiliated Hospital of Zhengzhou University) adopted "needle sealing therapy" for children with cerebral palsy (the full name is "point plus acupoint drug injection therapy"), and the hospital claimed to evaluate 381 children. The results showed that 190 cases, that is, nearly half, were normalized.

　　On October 21st, an article questioned the "needle sealing therapy" invented by Wan Guolan, the founder and honorary director of the Children’s Rehabilitation Department of the Third Affiliated Hospital of Zhengda, and the "needle sealing therapy" was pushed to the forefront. Sun Yong ‘an, chief physician of the Department of Neurology, Peking University First Hospital, said that "needle sealing therapy" is more of a gimmick, and even if it is effective, its effect is limited. Nerve injury is generally caused by congenital development or acquired injury. If it is cerebral palsy caused by poor nerve development in the embryo, even if there is some growth compensation, it is still difficult to completely cure it.

　　Cerebral palsy is difficult to treat, and there is no standard single treatment. Some experts said that we should not arbitrarily think that all self-created therapies are ineffective. Because medicine is a practical subject, it is advancing through constant exploration and trial, and some new therapies really need to break through the routine. However, the technology applied in clinic should be universally recognized and supported by evidence-based medicine. To carry out a clinical trial, first of all, the institutions involved and the researchers involved in the trial must have the qualifications to carry out clinical research; Second, it is necessary to carry out strict registration and filing, and strictly design the test plan, demonstration and modification; Third, it should be recognized by clinical trial management institutions and ethics committees; Fourth, the subjects should have the full right to know, the experimenter should ensure the safety of the subjects, and the subjects have the right to withdraw at any time during the treatment. As for the efficacy of the new therapy, it also needs a large sample of randomized double-blind controlled studies to verify it.

　　nine

　　At the dawn of treatment, "small molecular glue" can devour the pathogenic protein of Huntington’s disease

　　Involuntary dance-like movements, cognitive impairment and mental abnormality … … Huntington’s disease is one of the four major neurodegenerative diseases. Because the biochemical activity of the mutant Huntington’s protein (mHTT) causing the disease is unknown, it can’t be targeted. The traditional method of blocking the activity of the pathogenic protein by blocking agents is not suitable for the treatment of the disease.

　　At the end of October, researchers from Fudan University published their achievements in Nature, and found a "small molecular glue" that "devours" Huntington’s disease-causing protein through screening based on compound chips and cutting-edge optical methods, which is expected to bring new dawn to the clinical treatment of Huntington’s disease.

　　In the study, the team focused on controlling autophagy, an intracellular protein degradation pathway, to effectively reduce the level of mutant Huntington protein. In order to solve the problem of "self-injury", the team imagined to invent a kind of "small molecule glue", which can aim directly at the bull’s-eye, firmly stick LC3 and pathogenic protein (or other pathogenic substances) together, and then wrap the pathogenic protein into autophagy bodies for degradation. After screening, purification and a series of cell experiments, the research team obtained four kinds of "small molecular glues" that can bind LC3 and mutant Huntington protein.

　　According to team member Lu Bojun, at least two of these four compounds can cross the blood-brain barrier and directly reduce the level of mutant Huntington protein in the cerebral cortex and striatum of Huntington’s disease mice through low-dose intraperitoneal administration, without affecting the level of wild-type Huntington protein in brain tissue, and also improve the disease-related phenotype, which provides a breakthrough point for the development of oral or injection drugs for Huntington’s disease, and is expected to be applied to motor coordination disorders, facial twitching and muscle spasms.

　　10

　　"Aristocratic Drugs" Self-devalued Medical Insurance Drug List Negotiation to Reduce Patients’ Burden

　　Only when good drugs enter medical insurance can people finally get benefits.

　　In December, the National Health Insurance Bureau released the National Drug List of Basic Medical Insurance, Work Injury Insurance and Maternity Insurance in 2019 (hereinafter referred to as the Drug List). The results showed that 97 of the 150 negotiated drugs were successfully negotiated, and the average price dropped by 60.7%. This is also the largest since the establishment of the medical insurance system in China, with remarkable results.

　　During the negotiation, the National Medical Insurance Bureau spared no effort in bargaining. Take the shortlisted hepatitis C drugs as an example, four companies directly measure the quotation on the spot, and the quotation of each drug should be accurate to two decimal places. There are two quotations in total. If both of them fail to reach the psychological price of the medical insurance bureau, or exceed 15% of the medical insurance payment standard, they will be directly out. In the end, Ledipaviso fosbuvir tablets from Gilead Scientific Company, fosbuvir patavir and Elba Wegera Rive tablets from Merck were selected with an average decrease of 85%.

　　Xiong Xianjun, director of the Department of Medicine Management of the National Health Insurance Bureau, said that the significant reduction in drug costs is one of the results of this negotiation. By giving play to the role of the medical insurance department as a "strategic buyer", the drug costs will be greatly reduced by changing the price. A number of world-renowned "noble drugs" have been marked with "civilian prices", and imported drugs have basically given the lowest price in the world. It is conservatively estimated that through negotiation of price reduction and medical insurance reimbursement, the personal burden level of patients will be reduced to less than 20%, and individual drugs will be reduced to less than 5%.

Xinhuanet Beijing, January 30th (Reporter Liu Ying) The "green wave" of manufacturing industry has injected new impetus. On January 30th, the Ministry of Industry and Information Technology formulated and issued the Interim Measures for Gradient Cultivation and Management of Green Factories (hereinafter referred to as the Interim Measures). As an administrative normative document to carry out gradient cultivation and management of green factories in the future, the Interim Measures consists of 6 chapters and 27 articles, which specifically expounds the compilation principles, cultivation requirements, creation procedures, dynamic management, supporting mechanisms and other important contents, which will further lead the green manufacturing benchmark to play a leading role in demonstration and promote the green and low-carbon transformation and upgrading of industries and regions.

At the right time, gradually build a green manufacturing system.

Since the "Thirteenth Five-Year Plan", the Ministry of Industry and Information Technology has made great efforts to promote the construction of green factories, green industrial parks, green supply chains and green products with major projects and projects as the traction. Up to now, 5,095 green factories, 371 green industrial parks, 605 green supply chain management enterprises and nearly 35,000 green products have been cultivated at the national level, which has led to the establishment of more than 6,000 provincial and municipal green factories, nearly 300 green industrial parks and nearly 200 green supply chain management enterprises, and the level of green manufacturing in various industries and regions has been continuously improved. Generally speaking, a green manufacturing system based on green factories, green industrial parks, green supply chain management enterprises and green products is gradually being built, and the green manufacturing system with green factories as the core basic unit has become an important starting point for promoting green manufacturing in various places.

In this context, in order to speed up the construction of green manufacturing and service system, give full play to the basic and guiding role of green factories in the green and low-carbon transformation of manufacturing industry, accelerate the formation of standardized and long-term cultivation mechanism, and create a leading force in green manufacturing, the Ministry of Industry and Information Technology has formulated these measures according to the Outline of the 14th Five-Year Plan for National Economic and Social Development in People’s Republic of China (PRC) and the Long-term Target in 2035, the 14th Five-Year Plan for Industrial Green Development, and the peak carbon dioxide emissions Implementation Plan for Industrial Fields.

Dynamic management, establishing gradient cultivation mechanism in two dimensions

The Interim Measures plans to establish a gradient cultivation mechanism from two dimensions: vertically forming a standardized and unified green factory cultivation mechanism at the national, provincial and municipal levels; Horizontal through the green industrial park, green supply chain management enterprises to drive enterprises in the park, supply chain upstream and downstream to create green factories.

Specifically, the Interim Measures mainly includes six parts, including 27 clauses and 4 annexes.

Firstly, it is the general principle, which expounds the compilation purpose, related definitions of gradient cultivation of green factories, working principles and division of labor, platform construction and so on. It is clearly pointed out that green factory is the core implementation unit of green manufacturing, green industrial park is the platform for gathering green factories and green infrastructure, and green supply chain management enterprises are the key to drive the upstream and downstream factories of supply chain to implement green manufacturing. At the same time, the management platform for industrial energy conservation and green development (https://green.miit.gov.cn/, hereinafter referred to as the management platform) is a unified platform for gradient cultivation and management of green factories, aiming at creating a data platform for information sharing among provinces and cities.

The second part is the cultivation requirements, which mainly puts forward the general requirements for local cultivation, and defines the specific conditions for the cultivation of green factories, green industrial parks and green supply chain management enterprises. It is clearly put forward that the green industrial park should release the park green factory cultivation plan and organize enterprises in the park to create green factories; Green supply chain management enterprises should formulate suppliers’ green factory cultivation plans and promote suppliers to create green factories.

The third part is the creation procedure, which puts forward the working procedure, creation criteria and rejection conditions for applying to be included in the green manufacturing list at all levels. Enterprises and parks that meet the application conditions shall, on a voluntary basis, take the form of self-evaluation or entrust a third-party institution with evaluation ability to carry out evaluation according to relevant standards, and prepare an evaluation report and submit it through the management platform. In principle, green factories at the national level recommended by all localities should be included in the list of green factories at the provincial level. Green industrial parks at the national level should be industrial parks at or above the provincial level with a large number of green factories and a high proportion. Enterprises recommended by green supply chain management enterprises at the national level should be green factories at the national level in principle. The Ministry of Industry and Information Technology will organize experts to review the recommended list, determine the shortlist according to the principle of selecting the best among the best, demonstrating and leading, publicize it to the public, and release the annual green manufacturing list according to procedures.

The fourth part is dynamic management, which defines the way and process of supervision and management of green manufacturing list units and third-party institutions. By establishing a dynamic management mechanism of "what goes in and what goes out", the local competent departments of industry and information technology strengthen the guidance, supervision and inspection of enterprises or parks included in the green manufacturing list, conduct spot checks and rechecks from time to time, and continuously track and analyze the creation effect. At the same time, supervise and manage the third-party institutions doing business in the region, and report problems in time. Enterprises or parks in the green manufacturing list, if there are any changes, should be explained when filling in the dynamic management form.

The fifth part is the supporting mechanism, which puts forward the relevant responsibilities of the Ministry of Industry and Information Technology and its local competent departments, and clarifies the responsibilities of third-party institutions and green manufacturing list units in service, publicity and information disclosure. The Ministry of Industry and Information Technology will promote the "enterprise green code" that reflects the green development level of green factories, and cooperate with relevant departments to provide support to green manufacturing list units in terms of planning and layout, technological transformation, special fund application, government procurement, pilot demonstration, financial services and brand promotion. Local industrial and information departments should also take the gradient cultivation of green factories as the main starting point to promote the green and high-quality development of regional manufacturing. In addition, the Ministry of Industry and Information Technology encourages green factories to prepare green low-carbon development reports, green industrial parks to formulate green factory support policies, and green supply chain management enterprises to increase product procurement for green factories.

Finally, the supplementary provisions clarify the unit of document interpretation and the implementation time. The annexes mainly include the requirements for the third-party evaluation of green manufacturing, the evaluation requirements of green industrial parks and green supply chain management enterprises, and the dynamic management table of green manufacturing list units.

Multi-dimensional efforts to lead the majority of enterprises to practice green manufacturing

The Interim Measures also proposed that the gradient cultivation and management of green factories should follow the principles of enterprise subject, government guidance, standard guidance and comprehensive coverage. The Ministry of Industry and Information Technology will further optimize the external environment for enterprises’ green development, strengthen the supporting role of green manufacturing service system, speed up the formulation and promulgation of green manufacturing standards, promote potential cultivation target enterprises to continuously improve their work according to the requirements of standards, and lead the majority of enterprises to practice green manufacturing through cultivation and creation.

On the one hand, the Ministry of Industry and Information Technology guides and promotes the provincial industrial and information authorities to formulate detailed rules for the implementation of gradient cultivation and management of green factories in the region according to the Interim Measures, establish a gradient cultivation mechanism, and carry out the cultivation, management and recommendation of green factories, green industrial parks and green supply chain management enterprises in the region; On the other hand, the Ministry of Industry and Information Technology will continue to organize the annual green manufacturing list recommendation, cultivate a number of green factories, green industrial parks and green supply chain management enterprises at the national level every year, and strengthen publicity and implementation.

(January 30, 2024)

ExxonMobil Huizhou Ethylene Project has been fully constructed.

Hengli petrochemical construction is in full swing

China Shipping and Shell Phase III stepped up its preliminary construction.

……

in recent years

Large-scale project construction for Daya Bay

World-class green petrochemical industry highland injects majestic power

Daya Bay Development Zone for three consecutive years

Ranked first among the top 30 national chemical parks.

　　The 12th Party Congress of Huizhou proposed to build a world-class green petrochemical industry highland. The highland of world-class green petrochemical industry should have a world-class industrial scale and a world-class management service level. At present, Daya Bay Petrochemical Zone has gathered many world-class petrochemical giants. Since the first project-China Shipping Shell entered the station, Daya Bay Petrochemical Park has improved the corresponding facilities such as water supply, power supply, heat supply, gas supply and pipe corridor transportation for the project construction.service. With the settlement of large-scale projects, the development of Daya Bay Petrochemical Zone has been accelerated in an all-round way, and the management service level of the park has also been improved.

　　Since September 15, 2012, Daya Bay District has implemented the first phase of closed management of Daya Bay Petrochemical Zone with reference to the closed management of Jurong Island in Singapore, and completed the construction of 10.8 kilometers of barbed wire fence, three inspection gates of Ximenlou, Dongmenlou and Beimen, and about 10 kilometers of North Ring Road. Vehicles entering and leaving the petrochemical area shall implement the pass management system, and the certificates shall be in and out.

　　On September 1st, 2014, the second phase of closed management was implemented in the petrochemical zone, and a full-time management organization with public security as the main body was established. The park was isolated from the outside world by purse seine, and it was patrolled 24 hours a day to prevent and control vehicles and personnel from entering the park in violation of regulations.

　　After 20 years of development, Daya Bay Petrochemical Zone has been ranked first among the top 30 national chemical parks for three consecutive years. The year 2021 is the first year of the "14th Five-Year Plan", and the construction of large-scale projects in Daya Bay Petrochemical Zone has made great strides: the PTA project of Hengli Petrochemical (Huizhou) started, the ethylene project of ExxonMobil Huizhou was fully built, the second phase of CNOOC Shell was put into operation, and the third phase of CNOOC Shell was progressing smoothly … Daya Bay Petrochemical Zone is struggling to compete for the world-class petrochemical zone.

　　A world-class petrochemical park should have a world-class industrial scale and a world-class management service level. In recent years, municipal and district leaders have been leading teams to inspect domestic and international advanced petrochemical zones, and have extensively absorbed the experience in the construction and management of world-class parks:

　　Antwerp and Jurong Petrochemical Zone all adopt advanced park management, that is, land and operation are separated, and development agencies rent land to enterprises for operation and provide corresponding supporting services. Antwerp Petrochemical Zone has established a strict supervision system for the storage and transportation of dangerous goods. The managers of Rotterdam Petrochemical Zone do not aim at profit, and do not participate in market competition. Instead, they implement the government’s port management function through planning and construction. The rental income of their land or docks is all used for the construction of port infrastructure, and rolling development is implemented through land operation. Jurong Petrochemical Zone is the only one of the five parks in the first echelon of world-class parks that implements strict closed management, implements the most stringent safety and environmental protection standards in the world, has a strict security monitoring system in the trinity of land, sea and air, and has a world-class "plug and play" infrastructure …

　　"In comparison, Daya Bay Petrochemical Zone still has a lot of room for improvement in management services." The relevant person in charge of Daya Bay Petrochemical Zone Management Service Center said.

　　Apply what you have learned. In order to improve the intelligent level of resource allocation, optimization of process flow and process control, Daya Bay District started the construction of "Smart Park" project in December 2018. Using the new generation of information technology, the management system of "smart park" integrating safety, environmental protection, emergency response and energy will be established, and the main framework of "eight pillars" will be completed, which will build a framework system of "four beams", "eight pillars" and "wisdom+"smart park suitable for the world-class green petrochemical industry highland. At the same time, support the enterprises in the park to benchmark the international advanced standards, promote the upgrading of equipment and processes, actively explore and promote the application of 5G technology and the new mode of deep integration of "industrialization and modernization", build a collaborative innovation system of intelligent manufacturing oriented to the whole production process and the whole business chain, promote digital transformation, realize the whole life cycle supervision of hazardous chemicals, create an emergency rescue system with rapid response and efficient decision-making, and improve the intelligent management level of the park.

　　Up to now, the main framework of "Eight Columns" in the "Smart Park" project has been completed and some government applications have been realized. Next, the "cerebellum" of public security, safety supervision and fire protection will be connected to the "brain" one after another.

　　In addition, in order to improve the management services of the petrochemical area, Daya Bay District has accelerated the formulation of the planning for the pipeline corridors in the east and west and the public works and infrastructure construction in the west, promoted the integration of public works, and provided high-quality public works products and services for enterprises in the park. In the near future, we will focus on speeding up the infrastructure construction such as Oude public liquid terminal, expansion of China Shipping Shell Donglian terminal, ExxonMobil liquid chemical terminal and heavy cargo terminal, and Hengli petrochemical general terminal, and open up the logistics channels for the three major projects from raw material import to product export.

　　At the same time, accelerate the construction of the new West Gate Building, East Gate Building and North Gate Building in the petrochemical zone, and optimize and improve the fully enclosed management of the park. Accelerate the construction of sewage pipe network. Large vehicle lanes are planned for the petrochemical park and the North Ring Road, and dangerous chemicals vehicles enter and leave the petrochemical park from the North Gate Building in a unified way, which further strengthens the safety of the park.

　　In order to ensure the early landing, completion and production of large projects, Daya Bay District has set up special classes for major projects (such as Mobil Project Class, Hengli Project Class and CNOOC Shell Phase III Project Class, etc.), established an efficient coordination and communication network, carried out wall chart operations, and ensured the service guarantee for project construction.

　　"Civil air defense+physical defense+intellectual defense" to build the safety line of pipe gallery

　　On the morning of November 16th, 2021, the comprehensive construction activities of ExxonMobil Huizhou Ethylene Project with a total investment of about 10 billion US dollars were held simultaneously in Beijing, Houston, USA and Daya Bay, Huizhou, marking that the project entered the stage of comprehensive formal construction. In addition to the production facilities that have attracted much attention, the project also includes seven supporting projects, including the western comprehensive energy station, public pipe gallery, sewage treatment reconstruction and expansion project and other public supporting projects, which not only meet the needs of the project, but also further enhance the overall supporting service capacity of Daya Bay Petrochemical Park.

　　A few days ago, the reporter visited to understand the latest progress of the above three supporting projects.

　　The Western Comprehensive Energy Project is located in the west of Daya Bay Petrochemical Zone. It is reported that the project plans to build a 2× 600,000 kW gas-steam combined cycle cogeneration unit, which is a public heat source point in the western petrochemical area and the first integrated comprehensive energy demonstration base with hydrogen energy utilization in China.

　　The western comprehensive energy station project uses a series of new technologies, new processes and new materials to improve the comprehensive utilization rate of energy. According to the person in charge of Daya Bay Comprehensive Energy Co., Ltd., the main equipment of the project is 9HA.01 gas turbine, which is one of the most advanced gas turbines in the world at present, and the efficiency of the whole plant can be above 70% under the condition of heating, which is more than 4% higher than that of the F-class gas-steam combined cycle.

　　The project has reached a cooperation agreement with ExxonMobil Huizhou Ethylene Project to supply ultra-high pressure steam to ExxonMobil Huizhou Ethylene Project, and at the same time, eliminate the hydrogen-containing tail gas generated in its production process, fully realize the comprehensive utilization of energy, improve the energy conversion efficiency by more than 25% compared with traditional coal-fired and gas-fired boilers, and realize the emission of nitrogen oxides of 15ppm, and even realize the single-digit emission of nitrogen oxides after installing denitration devices.

　　At the same time, the project uses reclaimed water produced by water purification plant to realize comprehensive utilization of resources in the park; The central heating mode replaces the small-capacity boilers of heat-using enterprises in the west of the petrochemical park, which reduces the total carbon emission and other pollutant emissions and improves the intensive management efficiency of the petrochemical park.

　　In addition to the "hard core" technology, the building of the project itself is also very successful. In the comprehensive energy company, the reporter saw the renderings of the project-a building that blends with the surrounding environment, shining like a gem, making it hard to imagine that this is a power plant. The buildings that can be used in the main factory building, office building and other factories are all equipped with solar photovoltaic panels to reduce pollution and carbon, which reduces the auxiliary power consumption of the project by 0.1% and the annual power generation reaches 5 million kWh. The photovoltaic integration of buildings strongly recommended by the state has been perfectly reflected in this project. Focusing on the "30 60" goal of national peak carbon dioxide emissions and carbon neutrality, the company has made every effort to build the project into a comprehensive energy demonstration base with low carbon, advanced, high efficiency, intelligence, diversity and multi-energy.

　　The project was approved at the end of June last year and started construction; On December 9, 2021, the main building project of the project was started, and the boiler pile foundation project is being carried out in an orderly manner. The project is scheduled to be completed and put into operation in 2023. After the project is put into production, it is estimated that the annual power generation is about 4.7 billion kWh, the annual heat supply is about 11.12 million Ji Jiao, and the annual output value can reach more than 3 billion yuan.

　　In Daya Bay Petrochemical Zone, in addition to tower equipment and storage tanks, the most striking thing is the piece of pipe gallery, which, as the "arterial system" of the petrochemical zone, continuously transports materials to petrochemical enterprises. At present, a total of 18 kilometers of public pipe corridors have been built in Daya Bay Petrochemical Zone, connecting the material transportation corridors in the east and west of the petrochemical zone, covering all settled enterprises, including the first-phase pipe corridor, the first-phase pipe corridor, the Binhai No.7 Road pipe corridor, the Ikos pipe corridor, the Zhoubang pipe corridor and the western pipe corridor in the petrochemical zone. The public pipe gallery under construction is about 15 kilometers, including Daya Bay cross-sea public pipe gallery, Hengli section pipe gallery, underground power pipe gallery and other projects; The planned public pipe gallery is about 12 kilometers.

　　Li Weifeng, general manager of Huizhou Daya Bay Petrochemical Public Pipe Gallery Co., Ltd. (hereinafter referred to as "Pipe Gallery Company") introduced that in order to meet the public pipe gallery needs of Mobil Project and other settled enterprises, the pipe gallery company is building a Daya Bay cross-sea public pipe gallery project, with a total length of about 5.4 kilometers from Tsuen Wan Port Terminal (Tsuen Wan District) to Mobil Factory (Petrochemical District), with a total investment of about 500 million yuan, which involves crossing the sea area and requires the construction of a single span of 160 meters. In addition, the pipe gallery company plans to build a public pipe gallery such as the second phase of the western pipe gallery and the section from Binhai Avenue to Binhai 12. The construction content includes a sunken pipe gallery crossing Binhai Avenue. After the construction of the project, it can solve the problem of Mobil project’s synchronous guarantee for the use of public pipe gallery "at sea+above ground+underground".

　　With the continuous expansion of the scale of public pipe corridors in petrochemical areas, a smart pipe corridor system, which is designed by Shanghai Institute of Advanced Studies, Chinese Academy of Sciences and based on technologies such as Internet of Things, big data, cloud computing and artificial intelligence, has become a "magic weapon" to improve the safety management level of public pipe corridors.

　　In the central control room of the smart pipe gallery of the pipe gallery company, the reporter saw that the smart pipe gallery system integrates video monitoring system, gas detection system, anti-intrusion system and broadcasting system, and these systems can realize real-time linkage on the 3-D map modeled according to the real scene. When the staff clicks on one section of the pipe gallery, they can see the three-dimensional model of the pipe gallery. After zooming in several times, the fence and column number on the main body of the pipe gallery are clearly visible. Click on the pipeline on the pipe gallery, and they can also view the details of each pipeline, including customer unit, pipe diameter, length, direction, temperature and pressure, output unit, input unit, risk level and other information.

　　"These detailed data records are convenient for us to determine the specific location according to the pipe gallery signboard when there is an emergency in the pipe gallery, and notify the relevant units at the first time to start the corresponding emergency rescue plan." Zheng Duqin, assistant general manager of Guanlang Company, said that Guanlang Company adopted the safety concept of "civil air defense+physical defense+intellectual defense". In addition to the pipe gallery fence, Petrochemical Guanlang Company also invested in the construction of a 13.2-kilometer pipe gallery safety collision barrier, and arranged operators to regularly inspect the pipe gallery area and monitor it 24 hours a day.

　　After the petrochemical project is completed and put into production, sewage treatment is a big project. It is understood that after the first phase of ExxonMobil Huizhou Ethylene Project is completed and put into operation, the sewage generated by it needs to be treated by special environmental protection facilities. Its sewage treatment project is built by Huizhou Daya Bay Qingyuan Environmental Protection Co., Ltd. (hereinafter referred to as "Qingyuan Environmental Protection"). At present, the feasibility study, environmental assessment and preliminary design of the project have been completed, and it is planned to start in July 2022 and be completed and put into operation before the first quarter of 2024.

　　Qingyuan Environmental Protection is an important integrated supporting infrastructure and environmental protection "three simultaneities" construction project in Daya Bay Petrochemical Park (designed, constructed, put into production and used simultaneously with the main project). At present, Qingyuan Environmental Protection provides sewage treatment services for 46 enterprises stationed in the petrochemical park, with an average daily sewage treatment capacity of 8,000 cubic meters.

　　Peng Zhongting, deputy chief engineer of Qingyuan Environmental Protection, introduced that the new sewage treatment facility project is located in the existing plot of Qingyuan Environmental Protection, with a total investment of about 800 million yuan and an area of about 49,000 square meters. This project is used to treat production sewage, cooling tower sewage, high-salinity sewage and other sewage generated by ExxonMobil Huizhou Ethylene Phase I project, and the designed sewage treatment scale is 1120 cubic meters per hour.

　　Different from the previous sewage treatment facilities, part of the sewage of this project can be used as reuse water for Mobil after advanced treatment, and the reuse rate is 60% ~ 70% of the designed sewage treatment scale. Peng Zhongting said that the sewage recycling of petrochemical enterprises not only realizes the recycling of sewage, but also protects the water environment around the park.

The new semester is about to begin.

Summer and autumn alternate, crowds gather and children’s resistance is poor.

May cause a latent chicken pox outbreak

Vaccinate against chickenpox

Is the most effective means of prevention.

recent days

Municipal Health and Health Commission, Finance Bureau and Education Bureau

And the market supervision bureau jointly issued

"Forwarding about among children aged 7-12 in the province"

Develop live attenuated varicella vaccine

Notice of Free Vaccination Work

Will the city’s children aged 7-12

Included in the live attenuated varicella vaccine for free vaccination.

Questions and Answers about Chickenpox and Vaccination

Let’s watch it together

↓↓↓

What is chicken pox?

Chickenpox is an infectious disease caused by varicella-zoster virus with fever and rash as the main manifestations, which is mainly transmitted through respiratory droplets and direct contact.

Chickenpox is highly contagious and should be isolated immediately after infection. The isolation time is generally not less than 14 days after the onset from the beginning of rash to the scabbing of all varicella and herpes.

Both children and adults will be infected with chickenpox. At the time of initial infection, they all showed fever and rash. Adults get chickenpox, the symptoms are generally more serious than children, and the risk of complications is higher.

How to inquire about the vaccination history of children’s live attenuated varicella vaccine?

1. Find the child’s vaccination certificate and check the vaccination history of live attenuated varicella vaccine.

2. Parents can search for "Jiangsu Vaccination" in the Android APP Market/Apple App Store, download and install the app, and directly view it online after binding the children’s file information, saving time and effort. There are three points to note: 1. When binding files, the mobile phone number needs to be consistent with that kept by the children’s vaccination clinic. If the mobile phone number is changed, it needs to be updated at the children’s vaccination clinic before binding; 2. If children from other provinces need to go to the inoculation unit to complete the filing and then use the online inquiry function; 3. Children who have not registered their ID cards at the time of filing need to go to the children’s vaccination clinic to re-record their ID cards before they can view them.

3. Offline query

If the vaccination certificate is lost, parents can bring their children’s ID cards (or household registration books) directly to the children’s vaccination clinic in their jurisdiction to ask the staff, and they can also telephone the vaccination clinic in their jurisdiction.

Click on the text to view the information list of Yancheng Children’s Vaccination Clinic. Besides vaccination, what should I pay attention to in preventing chickenpox?

Step 1 control the source of infection

Patients with varicella need to be isolated from the eruption to the scab of all varicella herpes.

2. Cut off the route of transmission

Open the window regularly for ventilation, wash your hands frequently, gather less, and wear a mask when going out. Avoid contact with children with chickenpox and elderly people with herpes zoster.

3. Protect vulnerable groups

Exercise more at ordinary times, eat more nutritious food, work and rest regularly, get enough sleep and improve your resistance.

Source: Yancheng CDC Micro Health Nanjing Center for Disease Control and Prevention Yancheng released a comprehensive slide to see the next touch to read the original text.

Jiangsu Binhai released slide up to see the next one.

Original title: "Attention! Free vaccination! 》

Read the original text

　 　1905 movie network news　Directed by Peng Fa, the Hong Kong Peng brothers, written by Lei Zhilong, and starring Fox Xia and Jiao Xu, the youth love movie "Seventeen Years Old Will Hurt" held a launch conference in Zhuhai on May 14th. On that day, male and female leading actors Fox Xia, Jiao Xu, Luno and director Peng Fa attended the event, and the press conference revealed that Taiwan Province pop king Wang Leehom and Hong Kong popular idol Asa Charlene Choi would be invited to join us.

　 　 The poster released on the day of "seventeen years old who will hurt" is full of campus atmosphere. The names of the main characters on the blackboard and the cartoons flying all over the sky seem to bring people back to the lush campus. The film plays "Dream to quench thirst, youth to relieve pain", which combines inspirational and secondary culture, and the positive energy is bursting.

Hong Kong’s "ghost" talent director Peng Fa made a breakthrough in directing the youth love movie "Seventeen Years Old" for the first time.

　 　 Peng Brothers’ film series is popular in international film circles, especially director Peng Fa, who has won the award of film editing for many times. From the Hong Kong Golden Award, the Taiwan Golden Horse Award, the Toronto Film Festival in Canada and the Thailand Film Festival, they have all received high recognition and evaluation. Director Peng Fa has directed other films before, and won the Best Editing Award in the 18th Hong Kong Film Awards. Seventeen years old is the first time that Peng Fa directed a film with the theme of youth love. At the press conference, he said that he must make a different youth film and use pictures to explain the best youth story to everyone.

　 　 Producer Tang Shuning said on the spot that he was very much looking forward to Peng’s youth film. Choosing Peng Fa to direct this film is precisely because of the director’s unique understanding of youth films. I believe that the director will definitely subvert the inherent mode of domestic youth films and create a real Chinese youth film with his unique vision and splicing of pictures. At the same time, the producer Tang Shuning has high hopes for the film, and bluntly said that the box office will definitely exceed 300 million. He hoped that "Seventeen Years of Pain" would not only be recognized by the market, but also become a cornerstone of the rise of Ningbo movies.

Jiao Xu and Fox Xia joined hands to perform the second element of youth, and staged the pursuit of school scum.

　 　 Seventeen-year-old Who Will Hurt is a movie with the theme of youth love again by Hu Xia. The role has maintained the simple and warm style in the past. When Fox Xia talked about this film at the press conference, he was very much looking forward to cooperating with Jiao Xu and laughed that he grew up watching Jiao Xu’s works. In the film, Fox Xia plays a super schoolmaster, whose life begins to change under the strong attack of a school girl, and they play a funny and inspirational story of youth. At the same time, this year, Fox Xia will not only perform the leading role of "Seventeen Years Old Who Will Hurt", but also publish a new album for those who haven’t had any new works for a long time. Fox Xia even said that he is very much looking forward to singing the theme song of the movie, so we can wait and see.

　 　 Jiao Xu, as a star girl, has been making a lot of movies since her debut. From her little boy and her uniformed sister to the thriller film "The Old House of Psyche VI" co-directed by Peng Fa, Jiao Xu’s performance has always made people feel bright. This time, I joined hands with director Peng Fa again to play the first heroine and perform romantic love. At the press conference, Jiao Xu was dressed in a plaid short skirt and two ponytail comic books were girly, which was very consistent with the heroine image of the film. Producers even admitted that the script was created with reference to the images of Jiao Xu and Fox Xia at the beginning of its creation, and it is expected that Xueba senior will encounter a second-generation girl who has a great brain hole and does things with great efficiency. Jiao Xu and director Peng Fajun both said that working together again is a familiar, fresh, intense and sweet experience, and everyone is looking forward to the final result.

Wang Leehom, the king of music creation, joined hands with Asa to support Director Peng.

　 　 Peng Fa, the final director of the conference, revealed that the film will be joined by King Wang Leehom and Queen Asa, and the atmosphere at the scene is high. Since 2013, Wang Leehom has been absent from the mainland big screen. Although he has also participated in Hollywood blockbusters, he has never been able to meet the mainland audience. At the invitation of director Peng Fa, he specially starred in this youth love movie. Apart from the script role Wang Leehom’s expectation, his role modeling is sure to make fans excited. Ah sa (Charlene Choi) has always been a pure and lovely image. Playing Jiao Xu’s teacher in this film is the strong backing of Jiao Xu’s road to dreams. The dedication of two idol superstars will surely set off the audience’s youthful nostalgia.

　 　 According to Chien Sun, the chief producer of the drama, the film "Seventeen Years Old Will Hurt" will be released nationwide in the summer of 2017, which will break the usual pattern of domestic youth films and tell the youth stories of young people from the perspective of young people.

Today, Xiaobian picked a car and introduced it to everyone. It is. Let’s get to know each other.

First look at the appearance of the Pentium pony. The front of the Pentium pony looks very round and sporty. Combined with headlights, the details are exquisite. The car is equipped with etc. Come to the side of the car, the car body size is 3000MM*1510MM*1630MM, the car uses clean lines, the car side gives a very capable feeling, with large-sized thick-walled tires, eye-catching shape. Looking back, the rear of the car echoes the front face, and the taillights are very young and fashionable. Overall, they are quite atmospheric.

When I came to the Pentium pony car, the interior of the Pentium pony adopted a domineering shape, and the overall shape was remarkable. The steering wheel of the car is very in line with the interior style and made of plastic, giving people an impulse to control it. Take a look at the central control. The design of the center console is reasonable, which makes the interior style impressive, and the overall design of the central control is remarkable. Let’s look at the dashboard and seats again. They look dignified. The car uses a fabric seat, which is wide and thick, further improving the comfort of the occupants.

Pentium pony matched gearbox, 20KW, 85N.m, with good power performance.

The performance of the space in the trunk of Pentium Pony is relatively good, the opening size is in line with its positioning, and the family’s storage needs can be met. In addition, the car is equipped with anti-lock braking (ABS), braking force distribution (EBD), main driving airbag and other safety configurations.

What’s your main impression of this car after reading the whole article? This class of cars can often give consideration to both cost performance and practicality, and is often considered by most consumers as the first choice when buying a car.

　　Since ancient times, Xiaoxiang has been magnificent, and Changsha is happy at that time. The lush Yuelu Mountain, the fiery red shrimp and the orange mango table are as colorful as the Orange Island fireworks staged every weekend-Changsha, a landscape city that creates happiness and happiness.

　　New Town Happiness Business and Happiness Changsha have met many times and are committed to creating a brand-new happiness experience for local residents. On December 27, 2019, another masterpiece of Xincheng Business in Changsha-Changsha High Speed Rail Wuyue Plaza will be grandly opened. On September 5th, on the occasion of the 112th countdown to the opening of the project, the appreciation meeting for the investment of Wuyue Plaza, a 2019 Changsha high-speed railway, was held grandly at the Intercontinental Beichen Hotel on the Xiangjiang River.

　　Huang Zhichun, executive deputy general manager of Xincheng Commercial Management Group’s South Operation Center, and Hu Lili, general manager of Xincheng Commercial Management Group’s South Operation Center, and other leaders of Xincheng Commercial Management Group, joined hands with more than 100 representatives of brand merchants and media reporters such as Yonghui Supermarket, Xingyi Studios, Starbucks, Haidilao, Watsons, Chow Tai Fook and Chef Fei to witness the new departure of Changsha High Speed Rail Wuyue Plaza.

　　Get together and chat, Wuyue Plaza and brand friends meet happily.

　　Through the floor-to-ceiling windows of the banquet hall of Beichen Intercontinental Hotel, the beautiful scenery of Xiangjiang River is unobstructed. Xincheng Commercial would like to thank the brand friends who have long supported the development of Wuyue Plaza in Changsha High-speed Railway. They talked about the present situation and future trend of Changsha’s commercial development, and were full of confidence in the development prospect of Wuyue Plaza, a high-speed railway in Changsha.

　　At the thank-you meeting, Hu Lili, general manager of the operation department of the Southern District Operation Center of Xincheng Commercial Management Group, delivered a speech. She said that with the expansion of the commercial territory of Xincheng, Wuyue Square has successfully laid out three Wuyue Square in Changsha, namely Songya Lake, Changsha High-speed Railway and Changsha Ningxiang. Wuyue Plaza of Changsha High-speed Railway is another benchmark commercial space in Changsha after Wuyue Plaza of Songya Lake. I believe that Wuyue Plaza of Changsha High-speed Railway will definitely enhance the prosperity and vitality of East Changsha business circle with excellent business experience after its opening on December 27th this year, and lead the regional commercial development.

　　Liu Hao, general manager of Wuyue Plaza of Changsha High-speed Railway, explained the highlights of Wuyue Plaza of Changsha High-speed Railway in detail in the subsequent project highlights analysis, which injected strong development confidence into the brand merchants present.

　　Chef Fei and representatives of two merchants in Xingyi Studios also expressed their trust in the commercial strength of the new town and affirmed the market influence of Wuyue Plaza at the thank-you meeting.

　　Sheng Weiwei, Director of National Development of Chef Fei, said that Chef Fei aims to create a new generation of Hunan-style catering, and will customize special stores for Wuyue Plaza of Changsha High-speed Railway. He hopes that under the operation of the professional business team of Xincheng, Chef Fei will give full play to his strengths and help Wuyue Plaza of Changsha High-speed Railway become another holy place for punching cards in online celebrity.

　　Wang Liye, general manager of Xingyi Studios Hunan Company, said that Xingyi Studios is very optimistic about the future development space of Changsha high-speed rail Wuyue Plaza, and will customize a new generation of studios with the core concept of world-class equipment, themed space design and quality and warm service for Changsha high-speed rail Wuyue Plaza.

　　It is precisely because of the support of many high-quality brands that the experience of Wuyue Plaza is more perfect. In the more than one year since the opening of Wuyue Plaza in Songya Lake, Changsha, Wuyue Plaza has cooperated with many brands in Changsha to create a happy Changsha and a happy Wuyue.

　　In order to thank the brand merchants who have supported the development of Wuyue Plaza for a long time, a special awarding session was also set up at this appreciation meeting.

　　Among them, Miss Bao&Mr. Xie, Papa White Bear’s parent-child restaurant, Haidilao, Tigos and MY Art BAR won the "Innovative Brand-Popular upstart Award".

　　Chef Fei, Watsons, Laojie Fish Mouth, KFC and Chow Tai Fook won the "Top Selling Brand-Gold Sucking Overlord Award".

　　Xiyu FUNLINK, Yonghui Supermarket, Miss Six, Starbucks and Calvin Klein jeans won the "Cooperative Brand-Close Partner Award".

　　On the road to the development of new town business, Wuyue Plaza and brand businesses have always been mutually beneficial and symbiotic, and have a win-win dance. In the future, the new town business will further establish a business ecological relationship of mutual respect and trust with brand merchants, and help Wuyue Plaza across the country to develop more harmoniously and stably.

　　Huang Zhichun, executive deputy general manager of the Southern District Operation Center of Xincheng Commercial Management Group, also said in the subsequent toast that the development road of Xincheng Commercial is far and long, and we look forward to happiness and common development with all brand merchants.

　　As scheduled, Changsha High-speed Rail Wuyue Plaza was grandly opened on December 27th.

　　Commerce develops according to cities, and cities prosper because of commerce. Wuyue Plaza of Changsha High-speed Railway will be grandly opened on December 27th this year. As a benchmark project for new city business to settle in Changsha, it will add a lot of color to the beautiful picture of happy Changsha.

　　Liu Hao, the general manager of Wuyue Plaza of Changsha High-speed Railway, made a detailed interpretation of the highlights of Wuyue Plaza of Changsha High-speed Railway in the project analysis, and shared the project progress, investment results and thoughts on the project operation period.

　　Liu Hao said that Wuyue Plaza, a high-speed rail in Changsha, is committed to upgrading the commercial consumption level of Wuhan-Guangzhou business circle in Changsha and even East Changsha, rewriting the commercial pattern of East Changsha, and becoming the trend vane of Changsha’s commercial development in the next decade.

　　Wuyue Plaza of Changsha High-speed Railway has a total construction area of about 350,000 square meters. It is a large-scale commercial complex integrating shopping center, theme commercial pedestrian street, boutique residence and senior apartment, with the shopping center covering an area of 100,000 square meters. The project takes "nature and humanity, art and technology, socialization and experience" as its core, and aims to create an immersive and experiential commercial complex in East Changsha with a sense of scene experience, innovative business format and operational vitality.

　　In terms of brand introduction, Wuyue Plaza of Changsha High-speed Railway will integrate fashion clothes, fashionable catering, jewelry and shoes, children’s play, leisure and entertainment, cultural and creative experience and other functional combinations to meet consumers’ multi-level and compound consumption needs such as "one-stop shopping, one-leisure, one-day shopping and meeting people at any time".

　　Liu Hao said that at present, the completion rate of investment promotion of the project has reached 86%, and it has been decided to introduce the main store brands such as YinJim, the first store in fashion fitness Hunan, Xingyi Studios equipped with Sony StarX Cinema, Yonghui Supermarket, a large video game club, Star Century Video Games, the first bar KTV charm KTV, and how wonderful the parent-child growth paradise is. There are also fashion department store Memorial Day department store, life collection store FUNLINK, local leading brand Tongcheng Electric Appliance, children’s brain development brand Qitianzhen, one-stop service brand king of the children for mother and baby, and the first Huawei smart life museum in Hunan. Well-known catering brands such as Haidilao, Xibei Youmian Village, Chef Fei and Modern China Tea Shop have also been confirmed.

　　Under the introduction of Liu Hao, the brand owners have a very clear understanding of the development status and future planning of Changsha Wuyue Plaza. Wuyue Plaza, a high-speed railway in Changsha, is bound to change the commercial pattern of East Changsha and the lifestyle of local residents with brand-new brands, sentimental design details and unique leisure and entertainment methods, and enhance the prosperity and vitality of the business circle.

　　Adhering to the development concept of "having feelings, not copying, and having scale", the new town business is booming. As of August 31st, Xincheng Commercial has laid out 119 Wuyue Plaza in 97 cities across the country. By the end of 2019, 64 Wuyue Plaza will be opened in Xincheng Commercial, and by 2020, more than 100 Wuyue Plaza will be opened and operated.

　　Changsha High-speed Rail Wuyue Plaza, as the 63rd new town commercial opening in China and the second Wuyue Plaza opening in Changsha, will surely bring a brand-new lifestyle and happy experience to Changsha residents with more innovative commercial space and content.

　　After the success of "The Place of Light, Yue Xiaoxiang" 2019 Changsha High-speed Railway Wuyue Plaza Investment Appreciation Meeting, the development of Changsha High-speed Railway Wuyue Plaza will enter a new stage. In 112 days, Changsha High-speed Railway Wuyue Plaza will be grandly opened. Let’s look forward to its brilliant bloom together, and also look forward to more and better encounters between new town business and happy Changsha.